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皮肤浅表脂肪瘤样痣:8 例报告。

Nevus lipomatosus cutaneous superficialis: Report of eight cases.

机构信息

Dermatology Unit, Mongi Slim Hospital, Sidi Daoud, Tunis, 2046 Tunisia.

出版信息

Dermatol Ther (Heidelb). 2011 Dec;1(2):25-30. doi: 10.1007/s13555-011-0006-y. Epub 2011 Sep 9.

Abstract

INTRODUCTION

Nevus lipomatosus cutaneous superficialis (NLCS) is a rare benign hamartomatous skin tumor characterized by dermal deposition of mature adipose tissue. It's classified in two types: the classical form with multiple soft, pedunculated, cerebriform papules and nodules that coalesce into plaques, and the solitary form that consists of a solitary papule or nodule. In this study, eight cases of NLCS are reported.

METHODS

The study was a retrospective case series including all patients with histopathologically documented NLCS who attended the Dermatology Department of Charles Nicolle hospital between January 1997 and December 2010. The objective of our study was to determine the epidemioclinical characteristics, the histopathologic features, and the treatment of this hamartoma. Patients included three males and five females aged between 7 and 41 years.

RESULTS

In four cases hamartoma was present since childhood, and in the other four cases it appeared in the third and fourth decades. Classical form was noted in seven cases and the solitary form in one case. Lesions involved limbs in four patients and trunk in four patients. Seven patients underwent surgical excision, and for one case no treatment was proposed.

CONCLUSION

The multiple or classical form is largely predominant in our study. Habitually, NLCS has an asymptomatic course. Treatment is usually not necessary unless for cosmetic reasons; surgical excision is curative and recurrence after is rare.

摘要

简介

皮肤浅表脂肪瘤性神经错构瘤(NLCS)是一种罕见的良性错构性皮肤肿瘤,其特征是真皮中存在成熟脂肪组织。它分为两型:经典型表现为多发性、柔软、有蒂、脑回状丘疹和结节融合成斑块,孤立型则由单个丘疹或结节组成。本研究报告了 8 例 NLCS。

方法

本研究为回顾性病例系列研究,纳入了 1997 年 1 月至 2010 年 12 月期间在 Charles Nicolle 医院皮肤科就诊并经组织病理学证实为 NLCS 的所有患者。我们的研究目的是确定该错构瘤的流行病学、临床特征和治疗方法。患者包括 3 名男性和 5 名女性,年龄 7 至 41 岁。

结果

4 例患者的错构瘤自儿童期即存在,另外 4 例则出现在第三和第四十年。7 例为经典型,1 例为孤立型。4 例病变累及四肢,4 例累及躯干。7 例患者行手术切除,1 例未予治疗。

结论

在我们的研究中,多发性或经典型占主导地位。NLCS 通常无症状,通常无需治疗,除非出于美容原因;手术切除是治愈性的,且复发罕见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1146/3721534/50efd4d7cef2/13555_2011_6_Fig1_HTML.jpg

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