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小儿脂肪瘤性病变的最新进展:临床病理、免疫组织化学及分子概述

Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview.

作者信息

Ameloot Eline, Cordier Fleur, Van Dorpe Jo, Creytens David

机构信息

Department of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.

Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.

出版信息

J Clin Med. 2022 Mar 31;11(7):1938. doi: 10.3390/jcm11071938.

Abstract

Lipomatous neoplasms are a rare entity in the pediatric population, comprising less than 10% of soft tissue tumors in the first two decades of life. Some characteristics of pediatric adipocytic tumors are analogous to their adult counterparts, some pediatric lipomatous lesions however harbor unique features. In recent years, there have been significant advances in the understanding of the pathogenesis and hence in the classification and treatment of pediatric adipocytic tumors. This literature-based article will provide a review of the presently known clinicopathological, immunohistochemical and molecular features of pediatric lipomatous lesions.

摘要

脂肪性肿瘤在儿科人群中是一种罕见的实体,在前二十年的生命中占软组织肿瘤的比例不到10%。儿科脂肪细胞性肿瘤的一些特征与成人同类肿瘤相似,然而一些儿科脂肪性病变具有独特的特征。近年来,在对儿科脂肪细胞性肿瘤发病机制的理解以及分类和治疗方面取得了重大进展。这篇基于文献的文章将对目前已知的儿科脂肪性病变的临床病理、免疫组化和分子特征进行综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9792/8999862/1218c6238e4b/jcm-11-01938-g001.jpg

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