Department of Health Care Management, Chang Gung University, Tao-Yuan, Taiwan.
Geriatr Gerontol Int. 2013 Jul;13(3):563-70. doi: 10.1111/j.1447-0594.2012.00935.x. Epub 2012 Sep 18.
To examine how diabetes in combination with cardiovascular diseases (hypertension, heart disease and stroke) and geriatric conditions (cognitive impairment and depressive symptoms) affects the odds of disability in older adults.
We analyzed data from a nationally representative sample of people aged 65 years and over (n=2727) participating in the 2005 National Health Interview Survey in Taiwan. A total of 473 participants had a history of self-reported physician diagnosed diabetes. Disability was defined as reporting limitations in one or more tasks of activities of daily living (ADL), instrumental activities of daily living (IADL) or general physical activities (GPA). The Mini-Mental State Examination was used to assess cognitive function. The Center for Epidemiologic Studies Depression Scale was used to assess depressive symptoms.
After adjustment for other factors, cardiovascular diseases and geriatric conditions independently contributed to the excess odds of disability among participants with diabetes. Participants who had diabetes combined with cardiovascular diseases and geriatric conditions had odds ratios for ADL, IADL and GPA disability of 18.02 (95% CI 5.13-63.34), 7.95 (95% CI 4.07-15.50) and 5.89 (95% CI 3.19-10.90), respectively.
Our results highlight the high prevalence of co-occurrence of cardiovascular diseases with geriatric conditions in people with diabetes. Furthermore, the combined presence of these diseases and conditions is strongly associated with an excess odds of disability. These findings highlight the critical importance of preventing cardiovascular disease morbidity, and improving depressed mood and cognitive function in order to reduce disability risk in older adults with diabetes.
探讨糖尿病合并心血管疾病(高血压、心脏病和中风)和老年病(认知障碍和抑郁症状)对老年人残疾的影响。
我们分析了来自台湾参加 2005 年全国健康访谈调查的 65 岁及以上人群(n=2727)的全国代表性样本数据。共有 473 名参与者有经医生诊断为糖尿病的病史。残疾定义为报告日常生活活动(ADL)、工具性日常生活活动(IADL)或一般身体活动(GPA)的一项或多项活动受限。使用简易精神状态检查评估认知功能。使用流行病学研究抑郁量表评估抑郁症状。
在调整其他因素后,心血管疾病和老年病独立导致糖尿病患者残疾的风险增加。患有糖尿病合并心血管疾病和老年病的参与者,在 ADL、IADL 和 GPA 残疾方面的优势比分别为 18.02(95%可信区间 5.13-63.34)、7.95(95%可信区间 4.07-15.50)和 5.89(95%可信区间 3.19-10.90)。
我们的研究结果强调了糖尿病患者中心血管疾病与老年病同时发生的高患病率。此外,这些疾病和情况的共同存在与残疾风险的增加密切相关。这些发现强调了预防心血管疾病发病率、改善抑郁情绪和认知功能对于降低老年糖尿病患者残疾风险的重要性。