Division of Geriatric Medicine Tours University Hospital Tours France.
EA4245 Transplantation, Immunologie, Inflammation Tours University Tours France.
J Am Heart Assoc. 2023 Jan 17;12(2):e026850. doi: 10.1161/JAHA.122.026850. Epub 2023 Jan 11.
As the population ages, the global cardiovascular disease burden will continue to increase, particularly among older adults. Increases in life expectancy and better cardiovascular care have significantly reshaped the epidemiology of cardiovascular disease and have created new patient profiles. The combination of older age, multiple comorbidities, polypharmacy, frailty, and adverse noncardiovascular outcomes is challenging our routine clinical practice in this field. In this review, we examine noncardiovascular factors that statistically interact in a relevant way with health status and quality of life in older people with cardiovascular disease. We focused on specific geriatric conditions (multimorbidity, polypharmacy, geriatric syndromes, and frailty) that are responsible for a major risk of functional decline and have an important impact on the overall prognosis in this patient population.
随着人口老龄化,全球心血管疾病负担将继续增加,尤其是在老年人中。预期寿命的延长和心血管疾病护理的改善极大地改变了心血管疾病的流行病学,并创造了新的患者特征。年龄增长、多种合并症、多种药物治疗、虚弱和不良的非心血管结局的结合,给我们在这一领域的常规临床实践带来了挑战。在这篇综述中,我们研究了与心血管疾病老年人的健康状况和生活质量以统计学方式相互作用的非心血管因素。我们专注于特定的老年病况(多种合并症、多种药物治疗、老年综合征和虚弱),这些状况是导致功能下降的主要风险因素,并对这一患者群体的整体预后有重要影响。