State Clinic of Dermatology, Hospital of Skin and Venereal Diseases, Delfon 124, 54643 Thessaloniki, Greece.
Br J Dermatol. 2013 Feb;168(2):284-8. doi: 10.1111/bjd.12044. Epub 2012 Nov 20.
Dermoscopy is useful in evaluating skin tumours, but its applicability also extends into the field of inflammatory skin disorders. Discoid lupus erythematosus (DLE) represents the most common subtype of cutaneous lupus erythematosus. While dermoscopy and videodermoscopy have been shown to aid the differentiation of scalp DLE from other causes of scarring alopecia, limited data exist concerning dermoscopic criteria of DLE in other locations, such as the face, trunk and extremities.
To describe the dermoscopic criteria observed in a series of patients with DLE located on areas other than the scalp, and to correlate them to the underlying histopathological alterations.
DLE lesions located on the face, trunk and extremities were dermoscopically and histopathologically examined. Selection of the dermoscopic variables included in the evaluation process was based on data in the available literature on DLE of the scalp and on our preliminary observations. Analysis of data was done with SPSS analysis software.
Fifty-five lesions from 37 patients with DLE were included in the study. Perifollicular whitish halo, follicular keratotic plugs and telangiectasias were the most common dermoscopic criteria. Statistical analysis revealed excellent correlation between dermoscopic and histopathological findings. Notably, a time-related alteration of dermoscopic features was observed.
The present study provides new insights into the dermoscopic variability of DLE located on the face, trunk and extremities.
皮肤镜检查在评估皮肤肿瘤方面非常有用，但它的适用性也扩展到了炎症性皮肤病领域。盘状红斑狼疮（DLE）是最常见的皮肤红斑狼疮亚型。虽然皮肤镜和视频皮肤镜检查已被证明有助于区分头皮 DLE 与其他瘢痕性脱发的原因，但关于面部、躯干和四肢等其他部位 DLE 的皮肤镜标准的数据有限。
描述一系列非头皮部位 DLE 患者的皮肤镜特征，并将其与潜在的组织病理学改变相关联。
对面部、躯干和四肢的 DLE 病变进行皮肤镜和组织病理学检查。评估过程中选择的皮肤镜变量是基于头皮 DLE 的现有文献数据和我们的初步观察。使用 SPSS 分析软件进行数据分析。
本研究共纳入 37 例 DLE 患者的 55 个病变。围绕毛囊的白色晕环、毛囊角化栓和毛细血管扩张是最常见的皮肤镜特征。统计分析显示皮肤镜和组织病理学结果之间具有极好的相关性。值得注意的是，观察到皮肤镜特征随时间的变化。
本研究为面部、躯干和四肢 DLE 的皮肤镜变异性提供了新的见解。
