Bhardwaj Shivani, Peter Dincy, George Leni, George Anu A, Mahabal Gauri D, Pulimood Susanne, Danda Debashish, Janardana Ramya
From the Department of Dermatology Venereology and Leprosy, Christian Medical College, Vellore, Tamil Nadu, India.
Department of Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
Indian J Dermatol. 2025 Jan-Feb;70(1):1-5. doi: 10.4103/ijd.ijd_514_23. Epub 2024 Dec 30.
Discoid lupus erythematosus (DLE) is a specific cutaneous manifestation of systemic lupus erythematosus (SLE), which results in scarring alopecia of the scalp.
A prospective cross-sectional observational study on scarring alopecia among SLE patients was done between September 2016 and August 2017. The clinical and trichoscopic patterns of scalp DLE among these patients were studied. The DLE lesions were categorised into active and inactive based on clinical features. Trichoscopy was done and photographs were obtained using a non-polarised videodermoscope.
There were 26 patients with scalp DLE, out of which 15 patients (57.69%) had active DLE and 11 (42.30%) had inactive DLE. The trichoscopic findings seen were structureless white areas, loss of follicular units, blue-grey dots and globules, follicular keratotic plugs and telangiectasia. The trichoscopic features seen in active versus inactive DLE were blue-grey dots and globules (93.33% vs 63.63%), structureless white areas (93.33% vs 90.90%), loss of follicular units (86.66% vs 72.72%) and follicular keratotic plugs (80% vs 45.45%), yellow dots with arborising vessels (33.33% vs 72.72%), exaggerated honeycomb pigmentation (46% vs 63.63%) and telangiectasia (66.67% vs 54.54%). Scaling ( = 0.033) and blue-grey dots ( = 0.021) were significantly higher in active and yellow dots with arborising vessels ( = 0.047) in inactive DLE.
On comparing trichoscopic features between active and inactive DLE scaling and blue-grey dots were significantly higher in active and yellow dots with arborising vessels in inactive DLE.
盘状红斑狼疮（DLE）是系统性红斑狼疮（SLE）的一种特殊皮肤表现，可导致头皮瘢痕性脱发。
于2016年9月至2017年8月对SLE患者的瘢痕性脱发进行了一项前瞻性横断面观察研究。研究了这些患者头皮DLE的临床和毛发镜表现。根据临床特征将DLE皮损分为活动期和非活动期。进行毛发镜检查，并使用非偏振视频皮肤镜获取照片。
有26例头皮DLE患者，其中15例（57.69%）为活动期DLE，11例（42.30%）为非活动期DLE。观察到的毛发镜表现有无结构白色区域、毛囊单位缺失、蓝灰色点和小球、毛囊角化栓和毛细血管扩张。活动期与非活动期DLE的毛发镜特征比较如下：蓝灰色点和小球（93.33%对63.63%）、无结构白色区域（93.33%对90.90%）、毛囊单位缺失（86.66%对72.72%）和毛囊角化栓（80%对45.45%）、有分支血管的黄色点（33.33%对72.72%）、夸张的蜂窝状色素沉着（46%对63.63%）和毛细血管扩张（66.67%对54.54%）。活动期的脱屑（P = 0.033）和蓝灰色点（P = 0.021）以及非活动期DLE中有分支血管的黄色点（P = 0.047）显著更高。
比较活动期和非活动期DLE的毛发镜特征，活动期的脱屑和蓝灰色点以及非活动期DLE中有分支血管的黄色点显著更高。
