Department of Obstetrics and Gynecology, University of Cukurova School of Medicine, Adana, Turkey.
Fetal Diagn Ther. 2013;33(1):36-40. doi: 10.1159/000341568. Epub 2012 Sep 19.
To evaluate the role of three-dimensional (3D) sonography in the prenatal detection of the upper pole in fetuses with spina bifida.
Women admitted to a tertiary center with pregnancies with isolated open spina bifida were enrolled in the study. All fetuses had 3D sonography to predict the lesion level. The exact lesion level was ascertained using radiography and/or autopsy following the delivery at term or abortion.
Forty-eight cases were eligible for this study. Twenty-eight fetuses were diagnosed in the second trimester and the lesion level was precisely predicted in 24 (86%) of them. In 14 (70%) of the 20 fetuses diagnosed in the last trimester, the level was accurately determined. The remaining 10 fetuses, from both the second and third trimesters, were found to have a lesion level that was within one segment of the predicted lesion level. The correct matching rate was 38/48 (79%), and agreement within one segment was achieved in all cases.
According to our data, 3D ultrasound is useful for the prenatal determination of lesion level in spina bifida, which is an important prognostic factor.
评估三维（3D）超声在产前检测伴有脊柱裂胎儿上极中的作用。
本研究纳入在三级中心就诊的单纯开放性脊柱裂妊娠女性。所有胎儿均行 3D 超声检查以预测病变水平。在足月分娩或流产后，通过 X 线摄影和/或尸检确定确切的病变水平。
本研究共纳入 48 例病例。28 例胎儿在孕中期被诊断，其中 24 例（86%）准确预测了病变水平。20 例在孕晚期被诊断的胎儿中，14 例（70%）准确确定了病变水平。其余 10 例来自孕中期和孕晚期的胎儿，其病变水平与预测病变水平相差一个节段。正确匹配率为 38/48（79%），所有病例均达到相差一个节段的一致程度。
根据我们的数据，3D 超声对产前确定脊柱裂病变水平有用，这是一个重要的预后因素。
