Institute of Applied Synthetic Chemistry, Vienna University of Technology, 1060 Wien, Austria.
Macromol Rapid Commun. 2012 Dec 13;33(23):2046-52. doi: 10.1002/marc.201200502. Epub 2012 Sep 17.
Vinyl carbonates have recently been identified as a suitable alternative to (meth)acrylates, especially due to the low irritancy and cytotoxicity of these monomers. The drawback of some vinyl carbonates containing abstractable hydrogens arises through their moderate reactivity compared with acrylates. Within this paper, we use the thiol-ene concept to enhance the photoreactivity of vinyl carbonates to a large extent to reach the level of those of similar acrylates. Mechanical properties of the final thiol-ene polymers were determined by nanoindentation. Furthermore, low toxicity of all components was confirmed by osteoblast cell culture experiments.
乙烯基碳酸酯最近被确定为（甲基）丙烯酸酯的合适替代品，特别是由于这些单体的低刺激性和细胞毒性。一些含有可提取氢的乙烯基碳酸酯的缺点是它们的反应性与丙烯酸酯相比适中。在本文中，我们使用硫醇-烯反应概念在很大程度上提高了乙烯基碳酸酯的光反应性，使其达到类似丙烯酸酯的水平。最终的硫醇-烯聚合物的机械性能通过纳米压痕法测定。此外，通过成骨细胞培养实验证实了所有成分的低毒性。
