分子捕获与释放：用光响应脂质体的光阱进行控制释放。
Molecular catch and release: controlled delivery using optical trapping with light-responsive liposomes.
机构信息
Department of Biomedical Engineering, University of Arizona, Tucson, 85721, USA.
出版信息
Adv Mater. 2012 Dec 11;24(47):6380-3. doi: 10.1002/adma.201202180. Epub 2012 Sep 18.
Abstract
Gold-coated liposomes are maneuvered using an optical trap to achieve precise delivery of encapsulated molecular cargo. Movement and payload release from these plasmon resonant nanocapsules are independently controlled using a pulsed trapping beam. This technology enables in vitro delivery of a payload to a selected cell and may be applied to the interrogation of individual cells within their biological microenvironment.
摘要
金包脂质体使用光阱来操纵，以实现封装分子货物的精确传递。使用脉冲捕获束独立控制这些等离子体共振纳米胶囊的运动和有效载荷释放。该技术能够将有效载荷递送到选定的细胞中，并且可以应用于在其生物微环境内对单个细胞进行询问。
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