Department of Microbiology, Universidad Peruana Cayetano Heredia, Lima, Peru.
Am J Trop Med Hyg. 2012 Nov;87(5):897-901. doi: 10.4269/ajtmh.2012.12-0067. Epub 2012 Sep 17.
Twenty cases of Dyphillobothrium pacificum (fish tapeworm) infections were prospectively studied to determine whether this tapeworm is associated with megaloblastic anemia, as commonly reported for D. latum infections. The most frequent symptoms were fatigue and mild abdominal pain, which were identified in approximately 66.6% of the 18 patients interviewed. Fourteen patients received treatment with niclosamide and all were cured. The other six patients spontaneously eliminated the tapeworms. One patient, who also had chronic diabetes and gastric atrophy, had low vitamin B12 levels and megaloblastic anemia. In all other patients, including three other patients with anemia, baseline vitamin B12 levels were in the reference range and did not significantly change when re-assessed three months later. Unlike D. latum, infection with D. pacificum is seldom associated with megaloblastic anemia or vitamin B12 deficit.
20 例阔节裂头绦虫（鱼绦虫）感染病例进行了前瞻性研究，以确定这种绦虫是否与巨幼细胞性贫血有关，因为通常报告的阔节裂头绦虫感染与巨幼细胞性贫血有关。在接受采访的 18 名患者中，约有 66.6%的患者出现疲劳和轻度腹痛等最常见的症状。14 名患者接受了氯硝柳胺治疗，均已治愈。另外 6 名患者自发性排出了绦虫。一名同时患有慢性糖尿病和胃萎缩的患者维生素 B12 水平较低，出现巨幼细胞性贫血。在所有其他患者中，包括另外 3 名贫血患者，基线维生素 B12 水平均在参考范围内，三个月后重新评估时并未显著变化。与阔节裂头绦虫不同，感染阔节裂头绦虫很少与巨幼细胞性贫血或维生素 B12 缺乏有关。
