Department of Physical Medicine and Rehabilitation, University of Pittsburgh School of Medicine, 201 Kaufmann Building, 3471 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA.
Muscle Nerve. 2012 Oct;46(4):535-9. doi: 10.1002/mus.23409.
Dysphagia is a common side effect after botulinum toxin injections for cervical dystonia, with an incidence of 10-40%, depending upon the study and dose used.
Our study consisted of 5 preselected women who met criteria for cervical dystonia and subsequent dysphagia after electromyography (EMG)-guided injections. Injections were performed with ultrasound (US) imaging, and the effects on swallowing were examined. Separately, sternocleidomastoid (SCM) thickness in healthy controls and treated patients was measured.
There were 34 episodes of dysphagia over 98 injection sessions using EMG guidance for a cumulative rate of 34.7%. Using US plus EMG guidance, there was 0% dysphagia across 27 injection sessions. SCM thickness was <1.1 cm.
US combined with EMG guidance eliminated recurrent dysphagia after botulinum toxin treatment, possibly by keeping the injectate within the SCM.
吞咽困难是肉毒毒素注射治疗颈肌张力障碍的常见副作用,发生率为 10-40%,具体取决于研究和使用的剂量。
我们的研究包括 5 名符合条件的女性,她们在肌电图(EMG)引导下注射肉毒毒素后出现吞咽困难。使用超声(US)成像进行注射,并检查吞咽的影响。此外,还测量了健康对照组和治疗组患者胸锁乳突肌(SCM)的厚度。
在 98 次使用 EMG 引导的注射中,共发生 34 次吞咽困难,累积发生率为 34.7%。使用 US 加 EMG 引导,27 次注射中无吞咽困难,发生率为 0%。SCM 厚度<1.1 厘米。
US 联合 EMG 引导可消除肉毒毒素治疗后吞咽困难的复发,可能是通过将注射物保留在 SCM 内。