Kosuge Yasushi, Hiramoto Jun, Morishima Hiroyuki, Tanaka Yuichiro, Hashimoto Takuo
Department of Neurosurgery, St, Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa, 216-8511, Japan.
J Med Case Rep. 2012 Sep 18;6:306. doi: 10.1186/1752-1947-6-306.
Pituicytoma is a rare neoplasm of the neurohypophysis. To the best of our knowledge there have been no reports of pituicytoma in which long-term magnetic resonance imaging observation was performed. We calculated the doubling time of the tumor volume and described the growth pattern of a pituicytoma.
A 52-year-old Japanese man with a history of decreased libido was found to have a sellar and suprasellar mass. He underwent transsphenoidal surgery, but only a small specimen was obtained because of intraoperative bleeding. The tentative histological diagnosis was schwannoma. He noticed bitemporal hemianopsia 7 years later. A follow-up magnetic resonance imaging disclosed a tumor volume doubling time of 3830 days. Transcranial gross-total tumor resection was performed. The lesion consisted of elongated and plump tumor cells that were arranged in a fascicular or storiform pattern and were positive for S-100 protein and focally positive for glial fibrillary acidic protein. The final histological diagnosis was pituicytoma.
Pituicytoma is a slow-growing tumor, but the growth rate may change during follow-up.
垂体细胞瘤是一种罕见的神经垂体肿瘤。据我们所知,尚无关于进行长期磁共振成像观察的垂体细胞瘤的报道。我们计算了肿瘤体积的倍增时间,并描述了一例垂体细胞瘤的生长模式。
一名52岁有性欲减退病史的日本男性被发现蝶鞍区及鞍上有肿块。他接受了经蝶窦手术,但因术中出血仅获取了少量标本。初步组织学诊断为神经鞘瘤。7年后他出现双颞侧偏盲。随访磁共振成像显示肿瘤体积倍增时间为3830天。进行了经颅肿瘤全切术。病变由细长且饱满的肿瘤细胞组成,呈束状或席纹状排列,S-100蛋白阳性,胶质纤维酸性蛋白局灶阳性。最终组织学诊断为垂体细胞瘤。
垂体细胞瘤是一种生长缓慢的肿瘤,但在随访过程中生长速率可能会改变。