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1例表现为囊性形成的垂体细胞瘤罕见病例。

A Rare Case of Pituicytoma Presenting Cystic Formation.

作者信息

Ha Young Soo, Lee Soo Eon, Park Sung Choon, Ahn Sung Yeol, Jung Yoon Yang

机构信息

Department of Neurosurgery, Myongji Hospital, Hanyang University College of Medicine, Goyang, Korea.

Department of Pathology, Myongji Hospital, Hanyang University College of Medicine, Goyang, Korea.

出版信息

Brain Tumor Res Treat. 2021 Oct;9(2):70-74. doi: 10.14791/btrt.2021.9.e11.

Abstract

Pituicytoma is a rare solid benign tumor of the sellar and/or suprasellar region originating from the pituicytes of the neurohypophysis or infundibulum, which is not differentiated from a pituitary adenoma that is diagnosed mostly in the sellar and/or suprasellar region. In addition, cystic tumors are very rare and have not been reported due to their solid and hypervascular natures. A 33-year-old man presented with a chronic headache which exacerbated recently. MRI was performed and revealed a cystic tumor in the sellar and suprasellar regions with a small parenchymal island in the cyst compressing the optic chiasm. The endoscopic endonasal transsphenoidal approach was used to remove the tumor. Immunohistochemical staining was positive for thyroid transcription factor 1, S-100 protein, and glial fibrillary acidic protein. The pituicytoma was diagnosed based on histologic findings. The authors review herein the literature on clinical presentation, diagnosis, surgical management, and outcome.

摘要

垂体细胞瘤是一种罕见的起源于神经垂体或漏斗部垂体细胞的鞍区和/或鞍上区实性良性肿瘤,它与大多在鞍区和/或鞍上区诊断出的垂体腺瘤难以区分。此外,囊性肿瘤非常罕见,因其实性和富血管性质尚未见报道。一名33岁男性患者出现慢性头痛,近期加重。进行了磁共振成像(MRI)检查,发现鞍区和鞍上区有一个囊性肿瘤,囊肿内有一个小的实质岛,压迫视交叉。采用鼻内镜经蝶窦入路切除肿瘤。免疫组织化学染色甲状腺转录因子1、S-100蛋白和胶质纤维酸性蛋白呈阳性。根据组织学检查结果诊断为垂体细胞瘤。作者在此回顾了关于临床表现、诊断、手术治疗及预后的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d01d/8561223/d478aa05f6c4/btrt-9-70-g001.jpg

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