Shim Hyuk Ki, Cha Seung Heon, Cho Won Ho, Park Sung-Hye
Department of Neurosurgery, Pusan National University School of Medicine, Pusan National University Hospital, Busan, Korea.
Department of Pathology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.
Brain Tumor Res Treat. 2017 Oct;5(2):110-115. doi: 10.14791/btrt.2017.5.2.110. Epub 2017 Oct 31.
A 19-year-old man presented with bitemporal hemianopsia and was found to have a large sellar and suprasellar tumor, resembling a pituitary macroadenoma. Emergency transsphenoidal approach was attempted because of rapid visual deterioration with headache. However, the approach was complicated and stopped by uncontrolled hemorrhage from the tumor. After conventional cerebral angiography and recognition of an unusual pathology, transcranial approach was achieved to prevent permanent visual loss. The final pathological diagnosis was pituicytoma with epithelioid features. Pituicytoma is a rare low-grade tumor (WHO Grade I) of pituicytes involving the sellar and suprasellar region, and originating from special glial cells of the neurohypophysis. Because of the high vascularity, the firm consistency, and invasion to surrounding neurovascular structures, a pituicytoma should be included in the differential diagnosis of a mass in the sellar and suprasellar area if the tumor shows high enhancement with vascular components. We report a case of rare pituicytoma mimicking a pituitary macroadenoma with massive hemorrhage to disturb surgery.
一名19岁男性因双侧颞侧偏盲就诊,检查发现鞍区及鞍上有一巨大肿瘤,类似垂体大腺瘤。由于视力迅速下降并伴有头痛,尝试进行急诊经蝶窦手术。然而,手术过程复杂,因肿瘤出血难以控制而被迫中止。在进行常规脑血管造影并明确了一种不寻常的病理情况后,采用经颅手术以防止永久性视力丧失。最终病理诊断为具有上皮样特征的垂体细胞瘤。垂体细胞瘤是一种罕见的低级别肿瘤(世界卫生组织一级),起源于神经垂体的特殊神经胶质细胞,累及鞍区和鞍上区域。由于其血管丰富、质地坚韧且侵犯周围神经血管结构,如果肿瘤在增强扫描时有血管成分且表现为明显强化,则在鞍区和鞍上区肿物的鉴别诊断中应考虑垂体细胞瘤。我们报告一例罕见的垂体细胞瘤,其表现类似垂体大腺瘤并伴有大量出血,导致手术受阻。