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与甲型流感感染相关的米勒-费雪综合征。

Miller Fisher syndrome associated with influenza A infection.

作者信息

Hara Makoto, Morita Akihiko, Ichihara Kazuaki, Kashima Yoji, Kamei Satoshi, Kuwahara Motoi, Kusunoki Susumu

机构信息

Division of Neurology, Department of Medicine, Nihon University School of Medicine, Japan.

出版信息

Intern Med. 2012;51(18):2621-3. doi: 10.2169/internalmedicine.51.7984. Epub 2012 Sep 15.

Abstract

A 36-year-old, previously healthy man presented with Miller Fisher syndrome (MFS) five days after he was diagnosed with an influenza A infection by a rapid antigen test. He had not received any recent vaccinations. He had no loss of consciousness. Bilateral ophthalmoplegia, blepharoptosis, areflexia, and ataxic gait were noted. One week after treatment with intravenous immunoglobulin, his ophthalmoplegia, blepharoptosis, and ataxic gait had gradually improved, and his deep tendon reflexes returned. Anti-GQ1b IgG antibodies were detected in his serum. There has been no previous report of postinfectious MFS following confirmed an influenza A infection in an adult.

摘要

一名36岁、既往健康的男性在通过快速抗原检测确诊甲型流感感染五天后出现米勒-费希尔综合征(MFS)。他近期未接种任何疫苗。他没有意识丧失。检查发现双侧眼肌麻痹、上睑下垂、反射消失和共济失调步态。静脉注射免疫球蛋白治疗一周后,他的眼肌麻痹、上睑下垂和共济失调步态逐渐改善,并且深部腱反射恢复。在他的血清中检测到抗GQ1b IgG抗体。此前尚无成人确诊甲型流感感染后发生感染后MFS的报告。

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