Medicine, Calderdale and Huddersfield NHS Foundation Trust, Calderdale Royal Hospital Salterhebble, Halifax, West Yorkshire HX30PW, UK.
Age Ageing. 2014 Jan;43(1):145-7. doi: 10.1093/ageing/aft134. Epub 2013 Sep 1.
We describe the case of an 85-year-old gentleman admitted with bilateral ptosis and complete bilateral ocular paralysis. Initial differential diagnoses included myasthenia gravis, diabetic cranial neuropathy, an ischaemic event and possible occult neoplasm. Investigations did not support any of the differentials and Miller Fisher syndrome (MFS) was considered. Anti-GQ1b IgG antibody was positive, supporting the possibility of anti-ganglioside syndrome. This gentleman was treated with intravenous immunoglobulin (IVIG) and made a full recovery.
我们描述了一位 85 岁男性的病例,他因双侧上睑下垂和完全性双侧眼肌瘫痪而入院。最初的鉴别诊断包括重症肌无力、糖尿病性颅神经病、缺血性事件和可能的隐匿性肿瘤。检查结果不支持任何鉴别诊断,因此考虑米勒费舍尔综合征(MFS)。抗 GQ1b IgG 抗体阳性,支持抗神经节苷脂综合征的可能性。该患者接受了静脉注射免疫球蛋白(IVIG)治疗,完全康复。