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[一名68岁男性,出现观念运动性失用和不完全性格斯特曼综合征,左半球有多个囊性病变]

[A 68 year-old man presenting ideomotor apraxia and incomplete Gerstmann syndrome with multiple cystic lesions in the left hemisphere].

作者信息

Miyaji Yosuke, Miyasaki Hidetake, Ning Zhang, Watanabe Daisuke, Suzuki Yume, Kuroiwa Yoshiyuki

机构信息

Department of Neurology, Chigasaki Municipal Hospital.

出版信息

Rinsho Shinkeigaku. 2012;52(9):681-4. doi: 10.5692/clinicalneurol.52.681.

Abstract

A 68-year-old man was referred to our hospital with tension-type headaches and a 1-year history of dementia. On neurologic examination, he had ideomotor apraxia and incomplete Gerstmann syndrome that was characterized by acalculia, agraphia, and finger agnosia. On imaging, multiple cystic lesions reported as "unusually dilated perivascular spaces" were observed along the medullary arteries in the left hemisphere; some of them had adjacent hyperintense areas in fluid attenuated inversion recovery images. We assumed that the multiple cystic lesions caused his higher cerebral dysfunction, because ideomotor apraxia and Gerstmann syndrome are usually indicative of a left parietal lobe lesion. MR spectroscopy in the lesion site revealed increased lactate. On MR angiography, the left middle cerebral artery and the left posterior cerebral artery were poorly visualized without localized stenosis. Technetium-99 bicisate single-photon emission computed tomography showed severely decreased cerebral blood flow in the left hemisphere. Electroencephalography showed slow waves in the left hemisphere.

摘要

一名68岁男性因紧张型头痛和1年痴呆病史被转诊至我院。神经系统检查时,他存在观念运动性失用症和不完全性格斯特曼综合征,其特征为失算症、失写症和手指失认症。影像学检查发现,左半球沿髓质动脉有多个囊性病变,报告为“异常扩张的血管周围间隙”;其中一些在液体衰减反转恢复图像中有相邻的高信号区。我们推测这些多个囊性病变导致了他的高级脑功能障碍,因为观念运动性失用症和格斯特曼综合征通常提示左顶叶病变。病变部位的磁共振波谱显示乳酸增加。磁共振血管造影显示,左大脑中动脉和左大脑后动脉显示不清,无局限性狭窄。锝-99双半胱乙酯单光子发射计算机断层扫描显示左半球脑血流量严重减少。脑电图显示左半球有慢波。

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