Department of Pediatrics, LLRM Medical College, Meerut 250102, India.
Indian J Pediatr. 2013 Mar;80(3):195-8. doi: 10.1007/s12098-012-0805-x. Epub 2012 Sep 19.
To compare reduction in incidence of feed intolerance in neonates born with meconium stained amniotic fluid (MSAF) by use of gastric lavage to those who did not receive lavage.
This Randomized controlled trial was conducted in all vigorous newborns delivered through MSAF, with birth weight ≥1800 g and gestation ≥34 wk. In the lavage group, gastric lavage with 10 ml/kg of normal saline was done.
Twelve neonates in the lavage group (n = 124) developed feed intolerance compared to 16 neonates in control group (n = 120), (p = .309; OR 0.69; 95%CI 0.27-1.58). No difference in any other morbidity was noted.
Gastric lavage in neonates with MSAF does not reduce feed intolerance, irrespective of thickness of MSAF and it confers no advantages.
比较对胎粪污染羊水(MSAF)新生儿进行洗胃与未洗胃,以降低喂养不耐受发生率。
本随机对照试验纳入所有经 MSAF 分娩、出生体重≥1800 g 且胎龄≥34 周的活力新生儿。在洗胃组中,用 10 ml/kg 的生理盐水进行洗胃。
在洗胃组(n=124)中有 12 名新生儿发生喂养不耐受,而在对照组(n=120)中有 16 名新生儿发生喂养不耐受(p=0.309;OR 0.69;95%CI 0.27-1.58)。其他发病率无差异。
无论 MSAF 的厚度如何,对 MSAF 新生儿进行洗胃并不能降低喂养不耐受的发生率,且无任何优势。