Sinha Pawan, Held Richard
46-4077, MIT Department of Brain and Cognitive Sciences 77 Massachusetts Avenue, Cambridge, MA 02139.
F1000 Med Rep. 2012;4:17. doi: 10.3410/M4-17. Epub 2012 Sep 5.
Cases of sight onset after extended periods of congenital blindness provide windows into visual development and brain plasticity. Such cases are extremely rare in the developed world. Here, we make the argument that in meeting a public health challenge in the developing world, that of providing treatment to curably blind children, we have the opportunity to have a beneficial impact on science and society simultaneously. A recent initiative, Project Prakash, is motivated by these twin goals. We briefly describe this effort, some of its early results, and also the caveats that need to be kept in mind when interpreting the findings.
先天性失明很长一段时间后恢复视力的病例为视觉发育和大脑可塑性研究提供了窗口。这类病例在发达国家极为罕见。在此,我们认为,在应对发展中国家的一项公共卫生挑战,即治疗可治愈的失明儿童时,我们有机会同时对科学和社会产生有益影响。最近的一项倡议“普拉卡什计划”就是受这两个目标的推动。我们简要介绍这项工作、它的一些早期成果,以及在解读研究结果时需要牢记的注意事项。