扁平苔藓与丙型肝炎病毒抗体之间关系的评估
Evaluation of Relationship between Lichen Planus and HCV Antibody.
作者信息
Taghavi Zenouz Ali, Mehdipour Masoumeh, Gholizadeh Narges, Naghili Behrooz, Jafari Heydarlou Mohammad
机构信息
Assistant Professor, Department of Oral Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
J Dent Res Dent Clin Dent Prospects. 2010 Winter;4(1):10-3. doi: 10.5681/joddd.2010.003. Epub 2010 Mar 14.
BACKGROUND AND AIMS
Lichen planus is a relatively common chronic mucocutaneaous disease with an unknown cause, and is considered a manifestation of cell-mediated immune response. Hepatitis C virus (HCV) and its subgroups have been associated with lichen planus in different geographic locations. The present study was undertaken to evaluate the prevalence of HCV antibody in patients with lichen planus in northwest Iran.
MATERIALS AND METHODS
This descriptive analytical study included 30 patients with cutaneous lichen planus, 30 pa-tients with oral lichen planus, and 30 healthy individuals as controls. Anti-HCV test was run for all the subjects. Descriptive statistics as well as chi-square test, to compare means in the three study groups, were applied to the data using SPSS 14.0 computer software.
RESULTS
Age and sex differences between the groups were not significant. No statistically significant differences were ob-served in anti-HCV test results between the groups (P = 0.50).
CONCLUSION
No statistically significant relationships were observed between lichen planus and HCV antibody in the studied samples.
背景与目的
扁平苔藓是一种相对常见的慢性黏膜皮肤疾病，病因不明，被认为是细胞介导免疫反应的一种表现。丙型肝炎病毒（HCV）及其亚组在不同地理位置与扁平苔藓有关联。本研究旨在评估伊朗西北部扁平苔藓患者中HCV抗体的流行情况。
材料与方法
这项描述性分析研究纳入了30例皮肤扁平苔藓患者、30例口腔扁平苔藓患者以及30名健康个体作为对照。对所有受试者进行抗HCV检测。使用SPSS 14.0计算机软件对数据进行描述性统计以及卡方检验，以比较三个研究组的均值。
结果
各组之间的年龄和性别差异不显著。各组抗HCV检测结果之间未观察到统计学上的显著差异（P = 0.50）。
结论
在所研究的样本中，未观察到扁平苔藓与HCV抗体之间存在统计学上的显著关系。
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