Nakahara Haruka, Yoshimura Eriko, Tsuda Yukiko, Murofushi Toshihisa
Department of Otolaryngology, Teikyo University School of Medicine Mizonokuchi Hospital, Kawasaki, Japan.
Acta Otolaryngol. 2013 Feb;133(2):144-9. doi: 10.3109/00016489.2012.720030. Epub 2012 Sep 19.
Utricular dysfunction in patients with posterior canal benign paroxysmal positional vertigo (pBPPV) was supported by findings for ocular vestibular evoked myogenic potential (oVEMP).
To evaluate the utricular and saccular function in patients with pBPPV.
This study focused on 12 patients definitively diagnosed with pBPPV showing typical nystagmus by Dix-Hallpike maneuver and 12 controls. In these subjects, oVEMPs and cVEMPs to air-conducted 500 Hz tone burst (125 dB SPL) were measured. The patients also underwent caloric tests.
More of the patients with pBPPV showed abnormal responses in oVEMPs by stimulation on their affected side than the controls, while the results of cVEMPs showed no significant differences between pBPPV patients and controls. The abnormal results for oVEMPs on the affected side showed a higher percentage than those for cVEMPs and caloric tests in pBPPV patients. There was no significant association between any of the tests. These findings support the possibility that oVEMP reflects the specific abnormal condition in pBPPV, i.e. that the urticular function in pBPPV patients was highly damaged.
眼震电图（oVEMP）的结果支持后半规管良性阵发性位置性眩晕（pBPPV）患者存在椭圆囊功能障碍。
评估pBPPV患者的椭圆囊和球囊功能。
本研究聚焦于12例经Dix-Hallpike手法检查显示典型眼震且确诊为pBPPV的患者以及12例对照者。对这些受试者测量了气导500Hz短纯音（125dB SPL）诱发的oVEMP和颈肌前庭诱发肌源性电位（cVEMP）。患者还接受了冷热试验。
与对照组相比，更多pBPPV患者患侧刺激时oVEMP反应异常，而pBPPV患者与对照组之间cVEMP结果无显著差异。pBPPV患者患侧oVEMP异常结果的百分比高于cVEMP和冷热试验。各项检查之间均无显著关联。这些发现支持oVEMP反映pBPPV特定异常情况的可能性，即pBPPV患者的椭圆囊功能严重受损。
