Dzudie A, Choukem S-P N, Adam A K, Kengne A P, Gouking P, Dehayem M, Kamdem F, Doualla M S, Joko H A, Lobe M E, Mbouende Y M, Luma H, Mbanya J C, Kingue S
Department of Internal Medicine, Douala General Hospital, Cameroon.
Cardiovasc J Afr. 2012 Nov;23(10):533-7. doi: 10.5830/CVJA-2012-054. Epub 2012 Sep 19.
This study assessed the prevalence and determinants of electrocardiographic abnormalities in a group of type 2 diabetes patients recruited from two referral centres in Cameroon.
A total of 420 patients (49% men) receiving chronic diabetes care at the Douala General and Yaoundé Central hospitals were included. Electrocardiographic abnormalities were investigated, identified and related to potential determinants, with logistic regressions.
The mean age and median duration of diagnosis were 56.7 years and four years, respectively. The main electrocardiographic aberrations (prevalence %) were: T-wave abnormalities (20.9%), Cornell product left ventricular hypertrophy (16.4%), arrhythmia (16.2%), ischaemic heart disease (13.6%), conduction defects (11.9%), QTc prolongation (10.2%) and ectopic beats (4.8%). Blood pressure variables were consistently associated with all electrocardiographic abnormalities. Diabetes-specific factors were associated with some abnormalities only.
Electrocardiographic aberrations in this population were dominated by repolarisation, conduction defects and left ventricular hypertrophy, and were more related to blood pressure than diabetes-specific factors.
本研究评估了从喀麦隆两个转诊中心招募的一组2型糖尿病患者心电图异常的患病率及其决定因素。
纳入了在杜阿拉综合医院和雅温得中心医院接受慢性糖尿病治疗的420例患者（49%为男性）。采用逻辑回归分析对心电图异常进行调查、识别并分析其与潜在决定因素的关系。
平均年龄和诊断中位时长分别为56.7岁和4年。主要的心电图异常（患病率%）为：T波异常（20.9%）、康奈尔乘积左心室肥厚（16.4%）、心律失常（16.2%）、缺血性心脏病（13.6%）、传导缺陷（11.9%）、QTc延长（10.2%）和异位搏动（4.8%）。血压变量与所有心电图异常均持续相关。糖尿病特异性因素仅与部分异常相关。
该人群的心电图异常以复极异常、传导缺陷和左心室肥厚为主，且与血压的关系比与糖尿病特异性因素的关系更为密切。
