Park Jin Hoon, Jeon Sang Ryong
Department of Neurological Surgery, Gangneung Asan Medical Center, University of Ulsan College of Medicine, Gangneung, Korea.
J Korean Neurosurg Soc. 2012 Jul;52(1):27-31. doi: 10.3340/jkns.2012.52.1.27. Epub 2012 Jul 31.
Although hydroxyapatite (HA) spacer has been used for laminoplasty, there have been no reports on factors associated with fusion and on the effects of HA shape.
During January 2004 and January 2010, 45 patients with compressive cervical myelopathy underwent midline-splitting open door laminoplasty with winged (33 cases) and wingless (12 cases) HAs by a single surgeon. Minimal and mean follow up times were 12 and 28.1 months, respectively. Japanese Orthopedic Association (JOA) score was used for clinical outcome measurement. Cervical X-rays were taken preoperatively, immediately post-operatively, and after 3, 6, and 12 months and computed tomography scans were performed preoperatively, immediately post-operatively and after 12 months. Cervical lordosis, canal dimension, fusion between lamina and HA, and affecting factors of fusion were analyzed.
All surgeries were performed on 142 levels, 99 in the winged and 43 in the wingless HA groups. JOA scores of the winged group changed from 10.4±2.94 to 13.3±2.35 and scores of the wingless group changed from 10.8±2.87 to 13.8±3.05. There was no significant difference on lordotic and canal dimensional change between two groups. Post-operative 12 month fusion rate between lamina and HA was significantly lower in the winged group (18.2 vs. 48.8% p=0.001). Multivariate analysis showed that ossification of the posterior longitudinal ligament, male gender, and wingless type HA were significantly associated with fusion.
Clinical outcome was similar in patients receiving winged and wingless HA, but the wingless type was associated with a higher rate of fusion between HA and lamina at 12 months post-operatively.
尽管羟基磷灰石(HA)间隔物已用于椎板成形术,但尚无关于融合相关因素及HA形状影响的报道。
2004年1月至2010年1月期间,45例压迫性颈椎病患者由同一位外科医生采用带翼(33例)和无翼(12例)HA行中线劈开开门式椎板成形术。最短和平均随访时间分别为12个月和28.1个月。采用日本骨科协会(JOA)评分评估临床疗效。术前、术后即刻、术后3、6和12个月拍摄颈椎X线片,术前、术后即刻和术后12个月进行计算机断层扫描。分析颈椎前凸、椎管尺寸、椎板与HA之间的融合情况以及融合的影响因素。
所有手术共涉及142个节段,带翼HA组99个节段,无翼HA组43个节段。带翼组JOA评分从10.4±2.94变为13.3±2.35,无翼组评分从10.8±2.87变为13.8±3.05。两组之间在颈椎前凸和椎管尺寸变化方面无显著差异。术后12个月时,带翼组椎板与HA之间的融合率显著低于无翼组(18.2%对48.8%,p = 0.001)。多因素分析显示,后纵韧带骨化、男性性别和无翼型HA与融合显著相关。
接受带翼和无翼HA的患者临床疗效相似,但无翼型在术后12个月时HA与椎板之间的融合率更高。