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腰椎间盘突出症保守治疗失败的预测因素。

Factors predicting failure of conservative treatment in lumbar-disc herniation.

作者信息

Sutheerayongprasert Chaiyuth, Paiboonsirijit Sompoch, Kuansongtham Verapan, Anuraklekha Surapong, Hiranyasthiti Nanthadej, Neti Sumroeng

机构信息

Bumrungrad Spine Institute, Bumrungrad International Hospital, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2012 May;95(5):674-80.

Abstract

OBJECTIVE

To explore factors predicting failure of conservative treatment in lumbar-disc herniation.

BACKGROUND

Sciatica due to lumbar-disc herniation is a common complaint of spine patients. Even though the natural course is favorable, surgery is necessary in at least 10% of cases. Current trends show surgery to be more cost-effective than prolonged conservative care. However; there is limited information about the usefulness of clinical and radiographic parameters to classify patients who are likely to fail conservative treatment.

MATERIAL AND METHOD

Medical records of patients diagnosed with lumbar-disc herniation between January 1, 2007 and December 31, 2009 were studied. The records of patients in conservative and surgery groups were compared, for clinical features, MRI results and treatment modalities.

RESULTS

Fifty cases (discectomy) and 50 controls (successful conservative treatment) were enrolled. Demographic data, presenting symptoms and physical examination did not differ apart from duration of symptoms. Logistic regression analysis did not find a significant association between percentage of canal compromised after controlling for disc-fragment size, duration of symptoms and types of disc herniation. However disc fragment size was strongly associated with surgical outcome (OR = 2.6). Duration of symptoms (OR = 1.2) and sequestered type of lesion (OR = 12.3) were associated with surgery in this model. The use of physiotherapy and epidural steroid injections was lower but the failure rate was higher.

CONCLUSION

Long-duration, sequestered herniation and large fragment are predictive of failure in the conservative treatment of lumbar-disc herniation.

摘要

目的

探讨预测腰椎间盘突出症保守治疗失败的因素。

背景

腰椎间盘突出症所致坐骨神经痛是脊柱疾病患者的常见主诉。尽管其自然病程良好,但至少10%的病例需要手术治疗。目前的趋势表明,手术比长期保守治疗更具成本效益。然而,关于临床和影像学参数对可能保守治疗失败的患者进行分类的有用性的信息有限。

材料与方法

研究2007年1月1日至2009年12月31日期间诊断为腰椎间盘突出症患者的病历。比较保守治疗组和手术组患者的临床特征、MRI结果和治疗方式。

结果

纳入50例(椎间盘切除术)和50例对照(保守治疗成功)。除症状持续时间外,人口统计学数据、出现的症状和体格检查无差异。在控制椎间盘碎片大小、症状持续时间和椎间盘突出类型后,逻辑回归分析未发现椎管受压百分比之间存在显著关联。然而,椎间盘碎片大小与手术结果密切相关(OR = 2.6)。在该模型中,症状持续时间(OR = 1.2)和游离型病变(OR = 12.3)与手术相关。物理治疗和硬膜外类固醇注射的使用较低,但失败率较高。

结论

长时间、游离型突出和大碎片可预测腰椎间盘突出症保守治疗失败。

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