d'Ercole Manuela, Innocenzi Gualtiero, Ricciardi Francesco, Bistazzoni Simona
Department of Neurosurgery, Fondazione Policlinico Universitario "A. Gemelli," Università Cattolica del Sacro Cuore, Roma, Italy.
Department of Neurosurgery, IRCCS Neuromed, Pozzilli (IS), Italy.
Int J Spine Surg. 2021 Jun;15(3):466-470. doi: 10.14444/8068. Epub 2021 May 7.
Lumbar disc herniation (LDH) is the most common cause of radiculopathy; patients with severe pain refractory to conservative management or neurological deficits are candidates to surgical procedures. Michigan State University (MSU) classification is a radiological codification considering both the size of the LDH and its medial to lateral location on the axial plane. The purpose of this retrospective study is to identify which kind of LDH, according to the MSU scheme, is more likely to cause a motor deficit.
We performed a retrospective analysis on data obtained from 114 patients treated with 117 lumbar microdiscectomies after failure of non-operative care. All patients underwent neurological and functional evaluation before and after surgery according to the following: Oswestry Disability Index, visual analog scale, and Japanese Orthopaedic Association back pain evaluation questionnaire. Magnetic resonance imaging proved that disc herniation was classified according to the MSU scheme and was correlated with motor disturbances expressed according to Medical Research Council grade.
Statistical analysis showed a significant correlation between the lateral location of disc herniation (preforaminal and extraforaminal LDH, respectively MSU B and MSU C) and the grade of muscle weakness, given that the LDH in these locations poorly responded to medical therapy and was at higher risk for motor deficit onset; no significant correlation with the size was observed.
Beyond standardization of radiologic description, MSU classification proved to be useful in definition of prognosis and possibly in selection of surgical candidates. However, these data should be confirmed by prospective studies on a larger sample of patients, also including those under way for conservative treatment.
腰椎间盘突出症(LDH)是神经根病最常见的病因;对于保守治疗难以缓解严重疼痛或存在神经功能缺损的患者,是手术治疗的候选对象。密歇根州立大学(MSU)分类是一种影像学编码,它同时考虑了LDH的大小及其在轴平面上从内侧到外侧的位置。这项回顾性研究的目的是根据MSU方案确定哪种类型的LDH更有可能导致运动功能缺损。
我们对114例非手术治疗失败后接受117次腰椎显微椎间盘切除术的患者的数据进行了回顾性分析。所有患者在手术前后均根据以下指标进行神经和功能评估:奥斯威斯利残疾指数、视觉模拟量表和日本骨科协会背痛评估问卷。磁共振成像证实椎间盘突出症是根据MSU方案分类的,并与根据医学研究委员会分级表示的运动障碍相关。
统计分析显示,椎间盘突出症的外侧位置(分别为椎间孔前和椎间孔外LDH,即MSU B和MSU C)与肌肉无力程度之间存在显著相关性,因为这些位置的LDH对药物治疗反应不佳,发生运动功能缺损的风险更高;未观察到与大小有显著相关性。
除了放射学描述的标准化外,MSU分类在预后定义以及可能在手术候选者的选择方面被证明是有用的。然而,这些数据应由对更大患者样本的前瞻性研究来证实,样本还应包括正在接受保守治疗的患者。