Chifamba Jephat, Chakanyuka Kudakwashe E, Longo-Mbenza Benjamin, Mahachi Carol B, Mufunda Jacob
Department of Physiology, University of Zimbabwe, College of Health Sciences, Mount Pleasant, Harare, Zimbabwe.
High Blood Press Cardiovasc Prev. 2012 Sep 1;19(3):123-7. doi: 10.1007/BF03262461.
The objective of the study was to compare blood pressure changes during exercise between low and normal birth weight young Black adults.
Eighty medical students in their first and second year who had neonatal clinic cards as proof of birth weight were included in the study. Resting blood pressures and heart rates were recorded. Participants then underwent a multistage 9-minute exercise stress test while blood pressure responses were recorded at 3-minute intervals. The study was conducted in the Department of Physiology, University of Zimbabwe, College of Health Sciences, Harare, Zimbabwe.
Of the 80 subjects recruited, 34 had low birth weight (LBW), 26 of these were female and 8 were male. The proportion of LBW individuals, 62% (n = 21), who developed exercise-induced hypertension (EIH) was significantly higher (p < 0.05) than the proportion of those with normal birth weight (NBW), 32% (n = 11). In addition to LBW being significantly associated with EIH (χ2 test p < 0.05, odds ratio 7.5) compared with NBW, the LBW group had a significantly higher (p < 0.05) and exaggerated systolic and diastolic response in stages I and II of the exercise protocol compared with the NBW group.
LBW was associated with EIH in these young Black adults.
本研究的目的是比较低出生体重和正常出生体重的年轻黑人成年人在运动期间的血压变化。
80名大一和大二的医学生参与了本研究,他们有新生儿诊所卡片作为出生体重的证明。记录静息血压和心率。然后参与者进行了一个9分钟的多阶段运动压力测试,同时每隔3分钟记录一次血压反应。该研究在津巴布韦哈拉雷健康科学学院的津巴布韦大学生理学系进行。
在招募的80名受试者中,34名出生体重低(LBW),其中26名是女性,8名是男性。出生体重低的个体中,62%(n = 21)发生运动诱发高血压(EIH)的比例显著高于出生体重正常(NBW)的个体,后者为32%(n = 11)(p < 0.05)。与NBW相比,除了LBW与EIH显著相关(χ2检验p < 0.05,优势比7.5)外,LBW组在运动方案的第一阶段和第二阶段的收缩压和舒张压反应显著更高(p < 0.05)且更夸张。
在这些年轻黑人成年人中,低出生体重与运动诱发高血压有关。