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与猪带绦虫囊尾蚴体外外翻相关的呼吸变化

Respiratory changes associated with the in vitro evagination of Taenia solium cysticerci.

作者信息

Cervantes-Vazquez M, Correa D, Merchant M, Hicks J J, Laclette J P

机构信息

Department of Immunology, U.N.A.M. Mexico, Distrito Federal, Mexico.

出版信息

J Parasitol. 1990 Feb;76(1):108-12.

PMID:2299516
Abstract

The metabolic adaptability of Taenia solium cysticerci was studied in vitro, by measuring their respiratory rate before, during, and after trypsin-induced evagination. Under aerobic conditions, the oxygen consumption increased about 40% during evagination of the cysticeri and returned to basal rates after the process was completed. The percentage of evagination induced by trypsin was not affected under anaerobic conditions or in the presence of respiratory poisons such as cyanide and carbon monoxide. These data indicate that cysticerci use either aerobic or anaerobic pathways according to oxygen availability in the environment. Results from experiments of irreversible respiratory poisoning using cyanide suggest the presence of an alternative respiratory chain. Proteolytic action of trypsin on a fibrous layer surrounding the invaginated larvae is suggested by histological evidence.

摘要

通过在体外测量猪带绦虫囊尾蚴在胰蛋白酶诱导外翻之前、期间和之后的呼吸速率,研究了其代谢适应性。在有氧条件下,囊尾蚴外翻期间耗氧量增加约40%,外翻过程完成后恢复到基础速率。在无氧条件下或存在氰化物和一氧化碳等呼吸毒物时,胰蛋白酶诱导的外翻百分比不受影响。这些数据表明,囊尾蚴根据环境中的氧气可用性使用有氧或无氧途径。使用氰化物进行不可逆呼吸中毒的实验结果表明存在替代呼吸链。组织学证据表明胰蛋白酶对内陷幼虫周围的纤维层有蛋白水解作用。

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