Tyumen State University of Russia, Semakova Street 10, 625003 Tyumen, Russian Federation.
Ecotoxicol Environ Saf. 2012 Nov;85:82-7. doi: 10.1016/j.ecoenv.2012.07.026. Epub 2012 Sep 17.
Cytogenetic analysis methods were used to study the developing embryos of the following four Coregonidae species: Coregonus peled (Gmelin), Coregonus lavaretus (Gmelin), Coregonus nasus (Pallas) and Coregonus muksun (Pallas). Spawners of these species were selected from rivers and lakes of the Tyumen region (Russia) with different levels of pollution. The variability of the chromosomal aberration rate was analyzed during a monitoring period of more than 20 years. The level of chromosomal mutability in the embryonic cells of these fishes was found to have steadily increased during the observation period (1989-2011). The higher frequency of chromosomal mutations at different stages of embryogenesis in broad whitefish, C. nasus (Pallas), was noted in comparison with other species. The possible use of chromosomal mutation frequency as an indicator (biomarker) to characterize the state of a population is discussed.
采用细胞遗传学分析方法研究了以下 4 种鱒科鱼类的胚胎发育：红大麻哈鱼（Gmelin）、湖红点鲑（Gmelin）、圆头欧鱒（Pallas）和金鳟（Pallas）。这些鱼类的产卵亲鱼选自俄罗斯秋明地区不同污染水平的河流和湖泊。在 20 多年的监测期间，分析了染色体畸变率的变化。在观察期间（1989-2011 年），发现这些鱼类胚胎细胞的染色体可变性水平稳步增加。与其他物种相比，在宽白鲑、圆头欧鱒（Pallas）的胚胎发生的不同阶段，染色体突变的频率更高。讨论了将染色体突变频率用作指示物（生物标志物）来描述种群状态的可能性。
