开发用于胃肠道动力研究的 AMR-ACB 阵列。

Development of an AMR-ACB array for gastrointestinal motility studies.

机构信息

Universidade Estadual Paulista, Botucatu, SP, Brazil.

出版信息

IEEE Trans Biomed Eng. 2012 Oct;59(10):2737-43. doi: 10.1109/TBME.2012.2208748.

DOI:10.1109/TBME.2012.2208748

Abstract

The association between anisotropic magnetoresistive (AMR) sensor and AC biosusceptometry (ACB) to evaluate gastrointestinal motility is presented. The AMR-ACB system was successfully characterized in a bench-top study, and in vivo results were compared with those obtained by means of simultaneous manometry. Both AMR-ACB and manometry techniques presented high temporal cross correlation between the two periodicals signals . The contraction frequencies using AMR-ACB were 73.9 ± 7.6 mHz and using manometry were 73.8 ± 7.9 mHz during the baseline . The amplitude of contraction using AMR-ACB was 396 ± 108 μT·s and using manometry were 540 ± 198 mmHg·s during the baseline. The amplitudes of signals for AMR-ACB and manometric recordings were similarly increased to 86.4% and 89.3% by neostigmine, and also decreased to 27.2% and 21.4% by hyoscine butylbromide in all animals, respectively. The AMR-ACB array is nonexpensive, portable, and has high-spatiotemporal resolution to provide helpful information about gastrointestinal tract.

摘要

本文介绍了各向异性磁阻（AMR）传感器与交流磁感（ACB）生物阻抗技术联合用于评估胃肠道动力的相关研究。在一项基于桌面的研究中，成功对 AMR-ACB 系统进行了特征描述，并将体内结果与同时进行的压力测量结果进行了比较。两种方法的周期性信号之间具有很高的时间交叉相关性。在基线期，使用 AMR-ACB 测量的收缩频率为 73.9 ± 7.6 mHz，使用压力测量的收缩频率为 73.8 ± 7.9 mHz。在基线期，使用 AMR-ACB 测量的收缩幅度为 396 ± 108 μT·s，使用压力测量的收缩幅度为 540 ± 198 mmHg·s。新斯的明可使 AMR-ACB 和压力记录的信号幅度分别增加到 86.4%和 89.3%，而氢溴酸东莨菪碱可使信号幅度分别降低到 27.2%和 21.4%。AMR-ACB 阵列价格低廉、便携、具有高时空分辨率，可提供有关胃肠道的有用信息。