年轻男性精索静脉曲张是老年男性腹股沟疝和慢性静脉疾病的危险因素：一项前瞻性队列研究的初步结果
Varicocele in younger as risk factor for inguinal hernia and for chronic venous disease in older: preliminary results of a prospective cohort study.
作者信息
Serra Raffaele, Buffone Gianluca, Costanzo Giuseppe, Montemurro Rossella, Perri Paolo, Damiano Rocco, de Franciscis Stefano
机构信息
Unit of Vascular Surgery, Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.
出版信息
Ann Vasc Surg. 2013 Apr;27(3):329-31. doi: 10.1016/j.avsg.2012.03.016. Epub 2012 Sep 19.
BACKGROUND
Varicocele, inguinal hernia, and chronic venous insufficiency are often associated. Varicocele has its maximum prevalence in younger age, whereas hernia and chronic venous disease appear later. The aim of this study was to analyze the relationship between these conditions.
METHODS
A prospective cohort study was conducted, consisting of two groups of male patients. Group A comprised patients with varicocele, whereas group B comprised those with problems other than varicocele. Both groups were followed over time and were assessed for the onset of signs and symptoms related to inguinal hernia and chronic venous disease.
RESULTS
Preliminary results showed a positive correlation between the presence of varicocele in younger and the possible risk of hernia and/or chronic venous disease in later age.
CONCLUSIONS
Preliminary results suggest that varicocele in younger age appears to be an early marker of progression for a connective tissue-related disease in later age.
背景
精索静脉曲张、腹股沟疝和慢性静脉功能不全常相关联。精索静脉曲张在年轻时患病率最高，而疝和慢性静脉疾病则在较晚时候出现。本研究的目的是分析这些病症之间的关系。
方法
进行了一项前瞻性队列研究，由两组男性患者组成。A组为精索静脉曲张患者，而B组为患有精索静脉曲张以外问题的患者。两组均随时间进行随访，并评估与腹股沟疝和慢性静脉疾病相关的体征和症状的发生情况。
结果
初步结果显示，年轻时存在精索静脉曲张与晚年发生疝和/或慢性静脉疾病的可能风险之间存在正相关。
结论
初步结果表明，年轻时的精索静脉曲张似乎是晚年结缔组织相关疾病进展的早期标志物。
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