Department of Radiology, Southmead Hospital, North Bristol NHS Trust, Westbury-on-Trym, Bristol, UK.
Clin Radiol. 2013 Mar;68(3):293-301. doi: 10.1016/j.crad.2012.07.007. Epub 2012 Sep 19.
Rheumatoid arthritis is a relatively common multisystem disease associated with significant mortality and morbidity. Thoracic disease, both pleural and pulmonary, is a frequent extra-articular manifestation of rheumatoid arthritis and responsible for approximately 20% of rheumatoid-associated mortality. Rheumatoid disease and its associated therapies can affect all compartments of the lung inciting a range of stereotyped pathological responses and it is not infrequent for multiple disease entities to co-exist. In some instances, development of pulmonary complications may precede typical rheumatological presentation of the disease and be the first indication of an underlying connective tissue disease. The spectrum of thoracic disease related to rheumatoid arthritis is reviewed.
类风湿关节炎是一种相对常见的多系统疾病,与较高的死亡率和发病率相关。胸壁疾病,包括胸膜和肺部,是类风湿关节炎常见的关节外表现,也是导致约 20%类风湿关节炎相关死亡的原因。类风湿疾病及其相关治疗可能会影响肺部的所有部位,引发一系列典型的病理反应,而且多种疾病实体同时存在的情况并不少见。在某些情况下,肺部并发症的发生可能先于疾病的典型风湿学表现,并成为潜在结缔组织疾病的第一个迹象。本文回顾了与类风湿关节炎相关的胸部疾病谱。