Gauhar Umair A, Gaffo Angelo L, Alarcón Graciela S
Division of Pulmonary and Critical Care Medicine, The University of Alabama at Birmingham, Birmingham, Alabama 35294-3408, USA.
Semin Respir Crit Care Med. 2007 Aug;28(4):430-40. doi: 10.1055/s-2007-985664.
Rheumatoid arthritis (RA) is a systemic disease, characterized by symmetric joint involvement, but it can also affect other organ systems, including the lungs. The better-known pulmonary manifestations of RA are interstitial lung disease, rheumatoid nodules, and pleural effusions. Less common manifestations include bronchiolitis obliterans and crycoarytenoid arthritis. Management of these conditions involves, by and large, supportive pulmonary care and control of the underlying articular process. Other pulmonary manifestations in RA patients can ensue as a result of the treatments used for it, mainly methotrexate. This article discusses the most common pulmonary manifestations of RA and their treatment. A discussion about the increasing impact that cigarette smoking is having on RA is also provided.
类风湿性关节炎（RA）是一种全身性疾病，其特征为对称性关节受累，但也可影响包括肺部在内的其他器官系统。RA较常见的肺部表现为间质性肺疾病、类风湿结节和胸腔积液。较不常见的表现包括闭塞性细支气管炎和环杓关节炎。这些病症的治疗总体上包括支持性肺部护理和对潜在关节病变的控制。RA患者的其他肺部表现可能是由用于治疗该病的药物（主要是甲氨蝶呤）引起的。本文讨论了RA最常见的肺部表现及其治疗方法。此外还讨论了吸烟对RA日益增加的影响。
