Yang Haidi, Zheng Yiqing, Chen Qiujian, Xiong Hao, Chen Bin, Zhang Zhigang, Huang Xiaoming, Peng Jieren
Department of Otorhinolaryngology, Head and Neck Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, China.
ORL J Otorhinolaryngol Relat Spec. 2012;74(5):235-9. doi: 10.1159/000342277. Epub 2012 Sep 21.
To evaluate the diagnostic value of narrow-band imaging (NBI) for the detection of nasopharyngeal carcinoma (NPC).
Prospective study.
Tertiary medical center.
Between December 2009 and June 2010, a total of 1,854 patients were examined by means of an electronic nasopharyngolaryngoscope equipped with conventional white light (WL) and an NBI system. The sensitivity, specificity and positive/negative predictive values for detecting NPC were calculated and compared.
Of these patients, 62 cases (3.34%) were pathologically confirmed as NPC. The sensitivity, specificity, positive predictive value and negative predictive value for detecting NPC significantly increased from 90.3, 75.4, 11.3 and 99.6% with WL up to 100, 99.2, 81.6 and 100% with NBI, respectively.
Our findings suggested that NBI endoscopy might serve as an ideal tool in the detection of NPC.
评估窄带成像（NBI）在鼻咽癌（NPC）检测中的诊断价值。
前瞻性研究。
三级医疗中心。
2009年12月至2010年6月期间，共有1854例患者通过配备传统白光（WL）和NBI系统的电子鼻咽喉镜进行检查。计算并比较检测NPC的敏感性、特异性及阳性/阴性预测值。
这些患者中，62例（3.34%）经病理确诊为NPC。检测NPC的敏感性、特异性、阳性预测值和阴性预测值分别从使用WL时的90.3%、75.4%、11.3%和99.6%显著提高到使用NBI时的100%、99.2%、81.6%和100%。
我们的研究结果表明，NBI内镜检查可能是检测NPC的理想工具。
