窄带成像技术在鼻咽癌检测中的诊断价值。
The diagnostic value of narrow-band imaging for the detection of nasopharyngeal carcinoma.
作者信息
Yang Haidi, Zheng Yiqing, Chen Qiujian, Xiong Hao, Chen Bin, Zhang Zhigang, Huang Xiaoming, Peng Jieren
机构信息
Department of Otorhinolaryngology, Head and Neck Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, China.
出版信息
ORL J Otorhinolaryngol Relat Spec. 2012;74(5):235-9. doi: 10.1159/000342277. Epub 2012 Sep 21.
OBJECTIVES
To evaluate the diagnostic value of narrow-band imaging (NBI) for the detection of nasopharyngeal carcinoma (NPC).
STUDY DESIGN
Prospective study.
SETTING
Tertiary medical center.
SUBJECTS AND METHODS
Between December 2009 and June 2010, a total of 1,854 patients were examined by means of an electronic nasopharyngolaryngoscope equipped with conventional white light (WL) and an NBI system. The sensitivity, specificity and positive/negative predictive values for detecting NPC were calculated and compared.
RESULTS
Of these patients, 62 cases (3.34%) were pathologically confirmed as NPC. The sensitivity, specificity, positive predictive value and negative predictive value for detecting NPC significantly increased from 90.3, 75.4, 11.3 and 99.6% with WL up to 100, 99.2, 81.6 and 100% with NBI, respectively.
CONCLUSION
Our findings suggested that NBI endoscopy might serve as an ideal tool in the detection of NPC.
目的
评估窄带成像（NBI）在鼻咽癌（NPC）检测中的诊断价值。
研究设计
前瞻性研究。
研究地点
三级医疗中心。
研究对象与方法
2009年12月至2010年6月期间，共有1854例患者通过配备传统白光（WL）和NBI系统的电子鼻咽喉镜进行检查。计算并比较检测NPC的敏感性、特异性及阳性/阴性预测值。
结果
这些患者中，62例（3.34%）经病理确诊为NPC。检测NPC的敏感性、特异性、阳性预测值和阴性预测值分别从使用WL时的90.3%、75.4%、11.3%和99.6%显著提高到使用NBI时的100%、99.2%、81.6%和100%。
结论
我们的研究结果表明，NBI内镜检查可能是检测NPC的理想工具。
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