Michel G, Gerbaulet A, Lhomme C, Castaigne D, Prade M
Département de chirurgie générale carcinologique de l'Institut Gustave-Roussy, Villejuif.
Rev Prat. 1990 Jan 1;40(1):26-30.
The therapeutic protocole used at the Gustave Roussy Institute for invasive epithelioma of the uterine cervix rests, for limited forms (T1B-T2 proximal), on combined radiology and surgery. This include the recently introduced supraradical lymphadenectomy extended to the lumboarotic lymph nodes, first-line surgery in young women to preserve the ovarian function and postoperative chemotherapy for extra-pelvic N+ forms. In extensive forms (distal T2 and T3), the treatment of choice still is radiotherapy with external irradiation associated with curietherapy. T3 forms with urinary tract involvement now benefit from interventional radiology techniques. The basic treatment of T4 forms involving the bladder and/or rectum remains radiotherapy, but wide surgical resection (exenteration) is still indicated in some cases. The treatment of particular forms (post-hysterectomy cervix, uterine prolapse, pregnancy) relies on techniques that are suitable for each individual situation.
古斯塔夫·鲁西研究所针对子宫颈浸润性上皮癌采用的治疗方案，对于局限型（T1B - T2近端），基于放射治疗与手术相结合。这包括最近引入的扩大至腰主动脉旁淋巴结的超根治性淋巴结切除术、针对年轻女性保留卵巢功能的一线手术以及盆腔外N+型的术后化疗。对于广泛型（远端T2和T3），首选治疗仍是外照射放疗联合腔内放疗。伴有泌尿道受累的T3型现在受益于介入放射学技术。累及膀胱和/或直肠的T4型的基本治疗仍是放疗，但在某些情况下仍需进行广泛手术切除（脏器清除术）。特殊类型（子宫切除术后宫颈、子宫脱垂、妊娠）的治疗依赖于适合每种个体情况的技术。
