Bellevicine Claudio, Malapelle Umberto, Iaccarino Antonino, Schettino Pietro, Napolitano Vincenzo, Zeppa Pio, Troncone Giancarlo
Department of Biomorfologic and Functional Sciences, University of Naples Federico II, Naples, Italy.
Diagn Cytopathol. 2013 Jan;41(1):77-80. doi: 10.1002/dc.22923. Epub 2012 Sep 25.
The foamy gland pattern (FGP) may impart to pancreatic ductal adenocarcinoma (PDA) a deceptively benign appearance. Thus, its diagnosis on FNA is challenging. A case of PDA with FGP, that was suspected on Diff Quik smears, diagnosed on cell-block preparation and confirmed by ancillary stains and molecular techniques, is here reported. The diagnostic interpretation of foamy atypical cells on direct smears may benefit from cell block preparation and from ancillary techniques.
泡沫状腺体型（FGP）可能会使胰腺导管腺癌（PDA）呈现出一种具有欺骗性的良性外观。因此，通过细针穿刺抽吸活检（FNA）对其进行诊断具有挑战性。本文报告了一例具有FGP的PDA病例，该病例在Diff Quik涂片上被怀疑，在细胞块制备上得以诊断，并通过辅助染色和分子技术得到证实。直接涂片上泡沫状非典型细胞的诊断性解读可能得益于细胞块制备和辅助技术。
