Manser T J, Warner J F
Department of Internal Medicine, Eastern Virginia Medical School, Norfolk.
South Med J. 1990 Jan;83(1):73-4. doi: 10.1097/00007611-199001000-00023.
Neuroleptic malignant syndrome occurred in a patient with AIDS being treated with prochlorperazine. We believe this to be the first report of this association. Recognition and specific treatment were delayed in part because of overlap in signs and symptoms of the underlying infectious process. The true incidence of prochlorperazine-induced NMS is unknown, and this reaction may be underrecognized in patients who often have other significant medical illnesses.
一名正在接受氯丙嗪治疗的艾滋病患者发生了抗精神病药恶性综合征。我们认为这是关于这种关联的首例报告。由于潜在感染过程的体征和症状存在重叠，识别和特异性治疗有所延迟。氯丙嗪诱发的抗精神病药恶性综合征的真实发病率尚不清楚，在常有其他严重内科疾病的患者中，这种反应可能未得到充分认识。
