Department of Neurology, University of Maryland School of Medicine, Program in Shock, Trauma, and Anesthesiology Research (STAR), R. Adams Cowley Shock Trauma Center, Baltimore, MD, USA.
Neurology. 2012 Sep 25;79(13 Suppl 1):S199-204. doi: 10.1212/WNL.0b013e31826958f4.
The purpose of this article is to review the literature on periprocedural blood pressure (BP) management in acute ischemic stroke and to establish guidelines regarding management of BP. These guidelines are drawn from available evidence and expert opinion. This article reviews the pathophysiologic considerations of BP in ischemic stroke. It also examines the natural history of BP changes during stroke, as well as data on induced BP reduction and hypertension, particularly in light of reperfusion therapy. Finally, the article reviews major ongoing clinical trials for BP management in this setting. Recommendations made in this article may serve as a benchmark for future research in BP management in this patient population.
本文旨在回顾急性缺血性脑卒中围手术期血压（BP）管理的文献，并制定BP 管理指南。这些指南是基于现有证据和专家意见制定的。本文回顾了 BP 在缺血性脑卒中中的病理生理考虑因素。它还检查了脑卒中期间 BP 变化的自然史，以及关于诱导性 BP 降低和高血压的数据，特别是考虑到再灌注治疗。最后，本文回顾了该治疗环境下 BP 管理的主要正在进行的临床试验。本文中的建议可以作为未来该患者人群 BP 管理研究的基准。
