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生长于伊朗的光滑绵参的生物活性。

Biological activities of Eremostachys laevigata Bunge. grown in Iran.

作者信息

Esmaeili Akbar

机构信息

Department of Chemical Engineering, North Tehran Branch, Islamic Azad University, Tehran, Iran.

出版信息

Pak J Pharm Sci. 2012 Oct;25(4):803-8.

Abstract

Essential oil from flowers, stems, and roots of Eremostachys laevigata Bunge. gathered in Iran was analyzed using gas chromatography (GC) and gas chromatography/mass spectroscopy (GC/MS), and 23, 21, and 9 compounds were identified, respectively. The primary components of all three oils were found to be 1,8-cineole, benzaldehyde, and piperitenone oxide: 18.3%, 18.7%, and 2.5%; 17.9%, 7.7%, and 63.3%; and 15.7%, 21.3%, and 1.2%, respectively. The oils derived from flowers and stems also contained cis-piperitone oxide as a major component (10.1% and 12.2%, respectively). E. laevigata oil showed antibacterial activity, particularly towards Gram-positive bacteria; additionally antioxidant activity was induced with IC(50) of flowers, stems and roots of E. laevigata (277.1, 495.0, and 212.6 μg/ml), respectively. Furthermore, under β-carotene-linoleic acid test assay the flower, stem, and root oils of E. laevigata had a high antibacterial effect.

摘要

对采集于伊朗的光滑绵参(Eremostachys laevigata Bunge.)花、茎和根中的挥发油进行气相色谱(GC)和气相色谱/质谱联用(GC/MS)分析,分别鉴定出23种、21种和9种化合物。发现这三种挥发油的主要成分均为1,8-桉叶素、苯甲醛和氧化胡椒酮:分别为18.3%、18.7%和2.5%;17.9%、7.7%和63.3%;以及15.7%、21.3%和1.2%。花和茎中提取的挥发油还含有顺式氧化胡椒酮作为主要成分(分别为10.1%和12.2%)。光滑绵参挥发油具有抗菌活性,尤其对革兰氏阳性菌;此外,光滑绵参花、茎和根的挥发油还具有抗氧化活性,其IC(50)分别为277.1、495.0和212.6 μg/ml。此外,在β-胡萝卜素-亚油酸试验中,光滑绵参的花、茎和根挥发油具有很高的抗菌效果。

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