Institute of Hydrobiology, Jinan University, Guangzhou 510632, China.
Mar Pollut Bull. 2012 Nov;64(11):2317-24. doi: 10.1016/j.marpolbul.2012.09.002. Epub 2012 Sep 23.
The impact of typical pollutants upon the fish-farming was assessed by use of a battery of biomarkers in two typical marine aquaculture regions in South China. Biotransformation parameters including 7-ethoxyresorufin-O-deethylase (EROD), aminopyrine N-demethylase (APND), erythromycin N-demethylase (ERND), glutathione-S-transferase (GST) and Malondialdehyde (MDA) were measured in five cultured fish species. Pollutants such as polycyclic aromatic hydrocarbon (PAHs), organochlorinated compounds (OCs), heavy metals and antibiotics (quinolones and sulfonamides) in sediments were characterized. Higher pollutant residue levels were observed in Dapeng Cove. EROD, APND and ERND activities were lower in fish from Dapeng Cove compared with fish from Hailing Island, while it is just on the contrary for GST and MDA. ERND, APND and GST showed sensitivity corresponding to different pollutants. Small fish species seemed to exhibit more sensitive to pollutants. The study further supports usefulness of multi-biomarker approach considering multiple species to define the effects of anthropogenic inputs in marine aquaculture systems.
本研究采用生物标志物技术，在华南地区两个典型的海水养殖区，评估了典型污染物对鱼类养殖的影响。在 5 种养殖鱼类中测定了生物转化参数，包括 7-乙氧基Resorufin-O-脱乙基酶（EROD）、氨基比林 N-去甲基酶（APND）、红霉素 N-去甲基酶（ERND）、谷胱甘肽-S-转移酶（GST）和丙二醛（MDA）。对沉积物中的多环芳烃（PAHs）、有机氯化合物（OCs）、重金属和抗生素（喹诺酮类和磺胺类）等污染物进行了特征描述。大鹏湾的污染物残留水平较高。与来自海陵岛的鱼类相比，大鹏湾鱼类的 EROD、APND 和 ERND 活性较低，而 GST 和 MDA 则相反。ERND、APND 和 GST 对不同污染物表现出敏感性。小鱼种似乎对污染物更敏感。该研究进一步支持了采用多生物标志物方法评估人为输入对海水养殖系统影响的有效性，同时考虑了多种物种。
