Reproductive Medical Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
J Assist Reprod Genet. 2012 Oct;29(10):1077-81. doi: 10.1007/s10815-012-9830-y. Epub 2012 Jul 20.
To explore the pregnancy outcomes of embryo transfer with D2 or D3 embryos in patients with poor ovarian response.
The pregnancy outcomes of 620 patients who had poor ovarian response and underwent the first in vitro fertilization-embryo transfer (IVF-ET) were retrospectively analyzed. Of the 620 cycles, all available fresh D2 embryos were used in 365 cycles (day 2 embryo transfer) and all available fresh D3 embryos were used in 255 cycles (day 3 embryo transfer) without superfluous embryos for freezing.
There was a significant difference in clinical pregnancy rate between day 2 (32.73 %) and day 3 (50.83 %) embryo transfer in younger than 35-year-old patients, but no significant differences in implantation rate, live birth rate and spontaneous abortion rate (P > 0.05). There were similar pregnancy outcomes between day 2 and 3 embryo transfer in 35-year and older patients.
D3 embryo transfer may have better pregnancy outcomes in younger than 35-year-old patients with poor ovarian response.
探讨卵巢反应不良患者移植 D2 或 D3 胚胎的妊娠结局。
回顾性分析 620 例卵巢反应不良患者首次体外受精-胚胎移植（IVF-ET）的妊娠结局。在 620 个周期中，365 个周期（D2 胚胎移植日）使用了所有可用的新鲜 D2 胚胎，255 个周期（D3 胚胎移植日）使用了所有可用的新鲜 D3 胚胎，没有多余的胚胎用于冷冻。
在年龄小于 35 岁的患者中，D2 日（32.73%）与 D3 日（50.83%）胚胎移植的临床妊娠率有显著差异，但胚胎种植率、活产率和自然流产率无显著差异（P>0.05）。在年龄大于等于 35 岁的患者中，D2 日与 D3 日胚胎移植的妊娠结局相似。
对于卵巢反应不良的年轻患者（年龄小于 35 岁），D3 胚胎移植可能具有更好的妊娠结局。
