Department of Surgery, Division of Frontier Medical Science Graduate School of Biochemical Sciences, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, Japan.
Surg Today. 2013 Apr;43(4):418-23. doi: 10.1007/s00595-012-0346-y. Epub 2012 Sep 27.
A 76-year-old male was referred for the treatment of liver tumors detected by abdominal computed tomography (CT). Dynamic CT revealed a low-density tumor with an irregularly enhanced rim in the left lateral sector, and a highly enhanced, well-circumscribed tumor in the caudate lobe, accompanied by dilation of the intrahepatic biliary ducts in the left lobe. Preoperative imaging studies led to the diagnosis of double cancers consisting of intrahepatic cholangiocarcinoma and hepatocellular carcinoma (HCC). Left hemihepatectomy with caudate lobectomy was performed. The postoperative course was uneventful. Microscopic evaluation revealed that the tumor in the left lateral sector was adenosquamous carcinoma (ASC), whereas that in the caudate lobe was HCC. This report presents the first case describing the resection of synchronous double cancers of primary hepatic ASC and HCC.
一位 76 岁男性因腹部计算机断层扫描 (CT) 发现肝脏肿瘤而就诊。动态 CT 显示左外侧叶有一个低密度肿瘤，边缘不规则增强，尾状叶有一个高度增强、边界清楚的肿瘤，伴有左叶肝内胆管扩张。术前影像学检查诊断为肝内胆管细胞癌和肝细胞癌 (HCC) 双癌。行左半肝切除加尾状叶切除术。术后过程顺利。显微镜评估显示左外侧叶肿瘤为腺鳞癌 (ASC)，而尾状叶肿瘤为 HCC。本报告首次描述了原发性肝 ASC 和 HCC 同步双癌的切除。
