Bioproducts Lab, Central Leather Research Institute, Adyar, Chennai, 600020, India.
J Mater Sci Mater Med. 2012 Dec;23(12):3083-95. doi: 10.1007/s10856-012-4765-5. Epub 2012 Sep 27.
Collagen was isolated from the chrome containing leather waste (CCLW) which is a major solid waste in leather industry. Composite films were made using sago starch (SG), soya protein (SY), and collagen (C) and were cross linked with glutaraldehyde (G).The films prepared were characterized for their physico chemical properties like tensile strength, infrared spectra, thermogravimetric analysis, surface morphology, and water absorption studies. Better mechanical properties and surface morphology were observed for SG-SY-G-C films compared to other films prepared using collagen. The composite films prepared were used as wound dressing material on the experimental wounds of rats and healing pattern was evaluated using planimetric, biochemical, and histopathological studies. These studies have revealed better wound healing capacity of SG-SY-G-C film and utilization of CCLW in the preparation of value added product like wound dressing material.
胶原蛋白是从制革工业中的主要固体废弃物——含铬皮革废物（CCLW）中分离出来的。使用西米淀粉（SG）、大豆蛋白（SY）和胶原蛋白（C）制成了复合薄膜，并使用戊二醛（G）进行交联。对所制备的薄膜进行了物理化学性质的表征，如拉伸强度、红外光谱、热重分析、表面形貌和吸水性研究。与使用胶原蛋白制备的其他薄膜相比，SG-SY-G-C 薄膜具有更好的力学性能和表面形貌。将制备的复合薄膜用作大鼠实验性伤口的敷料，并通过平面测量学、生物化学和组织病理学研究评估愈合模式。这些研究表明，SG-SY-G-C 薄膜具有更好的伤口愈合能力，并且可以利用 CCLW 制备附加值产品，如伤口敷料材料。
