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硬膜外类固醇注射治疗有症状的腰椎间盘突出症的有效性

Effectiveness of epidural steroid injection for the management of symptomatic herniated lumbar disc.

作者信息

Baral B K, Shrestha R R, Shrestha A B, Shrestha C K

机构信息

Department of Anaesthesiology and Critical Care, Norvic International Hospital, Kathmandu, Nepal.

出版信息

Nepal Med Coll J. 2011 Dec;13(4):303-7.

Abstract

Low-back pain is a common clinical presentation of herniated lumbar disc. This is the most common presenting complain of the young adults. The incidence of low back pain is high in our part of the world. The reason may be hilly terrain, difficult working and living environment. The initial treatment of low back pain is conservative. Epidural steroid injection (ESI) is being slowly established as a simple, effective and minimally invasive treatment modality. The aim of this study is to assess the effectiveness of epidural steroid injection for low back and radicular pain. This is a Prospective observational study. It was carried out on the patients presenting with the complain of low back and radicular pain due to herniated lumbar disc not responding to conservative treatment. All the patients of herniated lumbar disc were proven by Magnetic Resonance Imaging (MRI). Injection Methyl prednisolone 80 mg and 2 ml of 0.5% bupivacaine was diluted in 8 ml of normal saline and injected into the affected lumbar epidural space. The functional status of the patient and the severity of pain were evaluated before injection and after injection during the follow-up period by using Ostrewy disability index and visual analogue score. Sixty two patients received the epidural steroid injections, but only fifty patients came for regular follow up till six months. Among the fifty patients, 26 were male and 24 were female. The functional status and pain response of the patients were improved significantly during all the follow-up periods (p < 0.001). The success rate of this study was 81%. No major complications were encountered. The ESI is a simple, safe, effective and minimally invasive modality for the management of symptomatic herniated discs.

摘要

下腰痛是腰椎间盘突出症常见的临床表现。这是年轻成年人最常见的就诊主诉。在我们这个地区,下腰痛的发病率很高。原因可能是地形多山、工作和生活环境艰苦。下腰痛的初始治疗是保守治疗。硬膜外类固醇注射(ESI)正逐渐成为一种简单、有效且微创的治疗方式。本研究的目的是评估硬膜外类固醇注射治疗下腰痛和神经根性疼痛的有效性。这是一项前瞻性观察研究。研究对象为因腰椎间盘突出症导致下腰痛和神经根性疼痛且对保守治疗无反应的患者。所有腰椎间盘突出症患者均经磁共振成像(MRI)证实。将80毫克甲泼尼龙和2毫升0.5%布比卡因稀释于8毫升生理盐水中,注入受影响的腰椎硬膜外间隙。在随访期间,通过使用奥斯维残疾指数和视觉模拟评分,在注射前和注射后评估患者的功能状态和疼痛严重程度。62例患者接受了硬膜外类固醇注射,但只有50例患者定期随访至6个月。在这50例患者中,男性26例,女性24例。在所有随访期间,患者的功能状态和疼痛反应均有显著改善(p < 0.001)。本研究的成功率为81%。未出现重大并发症。硬膜外类固醇注射是一种简单、安全、有效且微创的治疗有症状椎间盘突出症的方式。

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