Taggart Ryan, Austin Brenda, Hans Eric, Hogan Daniel
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.
J Vet Emerg Crit Care (San Antonio). 2012 Apr;22(2):219-24. doi: 10.1111/j.1476-4431.2012.00729.x.
To evaluate the effect of temperature alterations on in vitro coagulation in healthy dogs using thromboelastography (TEG).
In vitro study.
University teaching hospital.
Six healthy purpose-bred laboratory dogs.
None.
Thromboelastograph tracings were created daily for all test subjects and used to generate control values for R, K, α, and MA. Control values were compared to test samples incubated at 42, 39, 36, 33, 30, and 27°C. At temperatures ≤ 30°C, a significant increase in K values and a significant decrease in the α values were noted. There were no significant differences detected for R and MA among any of the test temperatures.
Hypothermia results in in vitro coagulation changes in healthy dogs as determined by whole blood analysis using TEG. The data suggest that while clots may form more slowly at decreased temperatures, the ultimate strength of the clot appears unaffected.
使用血栓弹力图（TEG）评估温度变化对健康犬体外凝血的影响。
体外研究。
大学教学医院。
6只健康的专门培育的实验犬。
无。
每天为所有受试对象绘制血栓弹力图，并用于生成R、K、α和MA的对照值。将对照值与在42、39、36、33、30和27°C孵育的测试样本进行比较。在温度≤30°C时，K值显著增加，α值显著降低。在任何测试温度下，R和MA均未检测到显著差异。
通过使用TEG进行全血分析确定，低温会导致健康犬体外凝血发生变化。数据表明，虽然在温度降低时凝块形成可能更慢，但凝块的最终强度似乎未受影响。
