Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
J Clin Epidemiol. 2012 Nov;65(11):1133-43. doi: 10.1016/j.jclinepi.2012.07.002.
To summarize the findings of methodological studies on the RAND/University of California Los Angeles (RAND/UCLA) appropriateness method, which was developed to assess if variation in the use of surgical procedures is because of overuse and/or underuse.
A MEDLINE literature search was performed. Studies were included if they assessed the reliability or validity of the RAND/UCLA appropriateness method for a surgical procedure or the effect of altering panelist composition or eliminating in-person discussion between rating rounds. Information was abstracted on procedure, study design, and findings.
One thousand six hundred one titles were identified, and 37 met the inclusion criteria. The test-retest reliability is good to very good (kappa, 0.64-0.81) for total knee and hip joint replacement, coronary artery bypass grafting (CABG), and carotid endarterectomy (CEA). The interpanel reliability is moderate to very good (kappa, 0.52-0.83) for CABG and hysterectomy. Construct validity has been demonstrated by comparing the appropriateness method with guidelines and/or evidence-based approaches for endoscopy, colonoscopy, CABG, hysterectomy, and CEA. Predictive validity has been studied for cardiac revascularization, in which concordance with appropriateness classification is associated with better clinical outcomes.
Our findings support use of the appropriateness method to assess variation in the rates of the procedures studied by identifying overuse and underuse. Further methodological research should be conducted as appropriateness criteria are developed and implemented for a broader range of procedures.
总结 RAND/加州大学洛杉矶分校(RAND/UCLA)适宜性方法的方法学研究结果,该方法旨在评估手术程序使用的差异是否是由于过度使用和/或使用不足所致。
进行了 MEDLINE 文献检索。如果研究评估了 RAND/UCLA 适宜性方法对手术程序的可靠性或有效性,或者改变小组成员组成或消除评分轮次之间的面对面讨论对手术程序的影响,则将纳入研究。摘要中记录了程序、研究设计和发现。
确定了 1610 个标题,其中 37 个符合纳入标准。全膝关节和髋关节置换术、冠状动脉旁路移植术(CABG)和颈动脉内膜切除术(CEA)的测试重测可靠性良好至非常好(kappa,0.64-0.81)。CABG 和子宫切除术的组间可靠性为中度至非常好(kappa,0.52-0.83)。已经通过将适宜性方法与内镜、结肠镜检查、CABG、子宫切除术和 CEA 的指南和/或循证方法进行比较来证明构效关系的有效性。已经研究了心脏血运重建的预测有效性,其中与适宜性分类的一致性与更好的临床结果相关。
我们的研究结果支持使用适宜性方法来评估研究程序的使用率差异,以识别过度使用和使用不足。随着适宜性标准的制定和更广泛的手术程序的实施,应进一步进行方法学研究。