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根据适当使用标准评估的手术适宜性与腰椎退行性脊椎滑脱症手术后患者自评结局的相关性。

Association between the appropriateness of surgery, according to appropriate use criteria, and patient-rated outcomes after surgery for lumbar degenerative spondylolisthesis.

机构信息

Department of Teaching, Research and Development, Spine Center Division, Schulthess Klinik, Lengghalde 2, 8008, Zurich, Switzerland.

Center for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland.

出版信息

Eur Spine J. 2021 Apr;30(4):907-917. doi: 10.1007/s00586-021-06725-3. Epub 2021 Feb 11.

Abstract

INTRODUCTION

Treatment failures in spine surgery are often attributable to poor patient selection and the application of inappropriate treatment. We used published appropriate use criteria (AUC) to evaluate the appropriateness of surgery in a large group of patients operated for lumbar degenerative spondylolisthesis (LDS) and to evaluate its association with outcome.

METHODS

This was a retrospective analysis of prospectively collected outcome data from patients operated in our Spine Centre, 2005-2012. Appropriateness of surgery was judged based on the AUC. Patients had completed the multidimensional Core Outcome Measures Index (COMI) before surgery and at 3 months' and 1, 2 and 5 years' follow-up (FU).

RESULTS

In total, 448 patients (69.8 ± 9.6 years; 323 (72%) women) were eligible for inclusion and the AUC could be applied in 393 (88%) of these. Surgery was considered appropriate (A) in 234 (59%) of the patients, uncertain/equivocal (U) in 90 (23%) and inappropriate (I) in 69 (18%). A/U patients had significantly (p < 0.05) greater improvements in COMI than I patients at each FU time point. The minimal clinically important change (MCIC) score for COMI was reached by 82% A, 76% U and 54% I patients at 1-year FU (p < 0.001, I vs A and U); the odds of achieving MCIC were 3-4 times greater in A/U patients than in I patients.

CONCLUSIONS

The results suggest a relationship between appropriateness of surgery for LDS and the improvements in COMI score after surgery. The findings require confirmation in prospective studies that also include a control group of non-operated patients.

摘要

简介

脊柱手术治疗失败通常归因于患者选择不当和治疗方法不当。我们使用已发表的适宜性使用标准(AUC)来评估大量接受腰椎退行性滑脱(LDS)手术的患者手术的适宜性,并评估其与结果的关系。

方法

这是对我们脊柱中心 2005 年至 2012 年前瞻性收集的患者结果数据进行的回顾性分析。根据 AUC 判断手术的适宜性。患者在手术前以及术后 3 个月、1 年、2 年和 5 年随访时完成多维核心结局测量指标(COMI)。

结果

共有 448 名患者(69.8±9.6 岁;323 名[72%]女性)符合纳入标准,其中 393 名(88%)可应用 AUC。234 名(59%)患者的手术被认为是适宜的(A),90 名(23%)为不确定/模棱两可(U),69 名(18%)为不适当(I)。在每个随访时间点,A/U 患者的 COMI 改善显著(p<0.05)大于 I 患者。在 1 年随访时,82%的 A 组、76%的 U 组和 54%的 I 组患者达到了 COMI 的最小临床重要变化(MCIC)评分(p<0.001,I 与 A 和 U 相比);A/U 患者达到 MCIC 的可能性是 I 患者的 3-4 倍。

结论

结果表明,LDS 手术的适宜性与术后 COMI 评分的改善之间存在关系。这些发现需要在包括非手术对照组的前瞻性研究中得到证实。

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