Azabu University, Kanagawa, Japan.
Emerg Infect Dis. 2012 Oct;18(10):1633-5. doi: 10.3201/eid1810.120503.
In 2008 in Japan, 15/60 captive Japanese macaques died. Clostridium tetani was isolated from 1 monkey, and 11 had tetanus-specific symptoms. We conclude the outbreak resulted from severe environmental C. tetani contamination. Similar outbreaks could be prevented by vaccinating all monkeys, disinfecting housing areas/play equipment, replacing highly C. tetani-contaminated soil, and conducting epidemiologic surveys.
2008 年在日本，有 15/60 只圈养的日本猕猴死亡。从 1 只猴子中分离出破伤风梭菌，11 只猴子出现破伤风特异性症状。我们得出结论，此次疫情是由严重的环境破伤风梭菌污染引起的。通过给所有猴子接种疫苗、对饲养区/娱乐设备进行消毒、更换高度污染破伤风梭菌的土壤以及开展流行病学调查，可以预防类似的疫情爆发。
