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[食管疾病:胃食管反流病和巴雷特食管]

[Esophageal diseases: gastroesophageal reflux disease and Barrett's esophagus].

作者信息

Calvet Xavier, Villoria Albert

机构信息

Unitat de Malalties Digestives, Hospital de Sabadell, Corporació Sanitària Universitària Parc Taulí, Departament de Medicina, Universitat Autònoma de Barcelona, Sabadell, Barcelona, Spain.

出版信息

Gastroenterol Hepatol. 2012 Sep;35 Suppl 1:26-34. doi: 10.1016/S0210-5705(12)70031-6.

Abstract

Digestive Disease Week always offers interesting advances. Among the notable advances concerning gastroesophageal reflux disease (GERD) in the 2012 meeting were studies on its association with functional dyspepsia. Furthermore, novel data suggest that undetected reflux plays a role in certain extraesophageal diseases. We also discuss the potential utility of impedanciometry of the esophageal mucosa in the diagnosis of GERD and review the management and implications of lack of response to proton pump inhibitors. We also review promising new techniques for screening for esophageal adenocarcinoma in Barrett's esophagus and new data on the efficacy and durability of radiofrequency ablation as the treatment of choice in cases associated with dysplasia or neoplasia in situ.

摘要

消化疾病周总能带来有趣的进展。在2012年会议上,与胃食管反流病(GERD)相关的显著进展包括其与功能性消化不良关联的研究。此外,新数据表明未被检测到的反流在某些食管外疾病中起作用。我们还讨论了食管黏膜阻抗测量法在GERD诊断中的潜在效用,并回顾了对质子泵抑制剂无反应的处理及影响。我们还回顾了在巴雷特食管中筛查食管腺癌的有前景的新技术,以及关于射频消融作为发育异常或原位肿瘤相关病例首选治疗方法的疗效和持久性的新数据。

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