Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Genet Med. 2013 Mar;15(3):212-21. doi: 10.1038/gim.2012.118. Epub 2012 Sep 27.
The purpose of this study was to compare health behaviors and cancer screening among Californians with and without a family history of cancer.
We analyzed data from the 2005 California Health Interview Survey to ascertain cancer screening test use and to estimate the prevalence of health behaviors that may reduce the risk of cancer. We used logistic regression to control for demographic factors and health-care access.
Women with a family history of breast or ovarian cancer were more likely to be up to date with mammography as compared with women with no family history of cancer (odds ratio = 1.69, 95% confidence interval (1.39, 2.04)); their health behaviors were similar to other women. Men and women with a family history of colorectal cancer were more likely to be up to date with colorectal cancer screening as compared with individuals with no family history of cancer (odds ratio = 2.77, 95% confidence interval (2.20, 3.49)) but were less likely to have a body mass index <25 kg/m(2) (odds ratio = 0.80, 95% confidence interval (0.67, 0.94)).
Innovative methods are needed to encourage those with a moderate-to-strong familial risk for breast cancer and colorectal cancer to increase their physical activity levels, strive to maintain a healthy weight, quit smoking, and reduce alcohol use.Genet Med 2013:15(3):212-221.
本研究旨在比较有和无癌症家族史的加利福尼亚居民的健康行为和癌症筛查情况。
我们分析了 2005 年加利福尼亚健康访谈调查的数据，以确定癌症筛查测试的使用情况，并估计可能降低癌症风险的健康行为的流行率。我们使用逻辑回归来控制人口统计学因素和医疗保健的可及性。
与没有癌症家族史的女性相比，有乳腺癌或卵巢癌家族史的女性更有可能进行乳房 X 光检查（比值比=1.69，95%置信区间[1.39，2.04]）；她们的健康行为与其他女性相似。有结直肠癌家族史的男性和女性比没有癌症家族史的个体更有可能进行结直肠癌筛查（比值比=2.77，95%置信区间[2.20，3.49]），但更不可能有身体质量指数<25kg/m2（比值比=0.80，95%置信区间[0.67，0.94]）。
需要创新的方法来鼓励那些有中度至强烈乳腺癌和结直肠癌家族风险的人增加身体活动水平、努力保持健康体重、戒烟和减少饮酒。遗传医学 2013：15（3）：212-221。
