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感染艾滋病毒后血友病男孩的生长情况。

Growth in haemophilic boys after HIV infection.

作者信息

Pasi K J, Collins M A, Ewer A K, Hill F G

机构信息

Department of Haematology, Children's Hospital, Birmingham.

出版信息

Arch Dis Child. 1990 Jan;65(1):115-8. doi: 10.1136/adc.65.1.115.

Abstract

Although failure to thrive has been documented as a major problem in babies with congenital HIV infection, there is little information on whether HIV affects growth in older children who become infected with HIV. The growth of 27 haemophilic boys, in whom HIV seroconversion was recorded between 1981 and 1986, has been assessed to see if the pattern changed after seroconversion. Height and weight recordings were analysed over a mean period of 9.2 years with a mean duration from HIV seroconversion of 4.5 years (range 2 to 6 years). Height standard deviation scores and ratio of weight to 50th centile for chronological age were calculated. No significant change in growth pattern as judged by height and weight has been observed within this group of boys after HIV seroconversion. Growth assessment continues to be evaluated to see if further progression of HIV disease changes growth pattern in these boys.

摘要

尽管生长发育迟缓已被证明是先天性HIV感染婴儿的一个主要问题,但关于HIV是否会影响感染HIV的大龄儿童的生长发育,目前所知甚少。对27名患血友病男孩的生长发育情况进行了评估,这些男孩在1981年至1986年间记录了HIV血清转化情况,以观察血清转化后生长模式是否发生变化。在平均9.2年的时间里分析了身高和体重记录,从HIV血清转化到分析的平均时长为4.5年(范围为2至6年)。计算了身高标准差分数和按实足年龄计算的体重与第50百分位数的比值。在这组男孩中,HIV血清转化后,根据身高和体重判断,生长模式没有显著变化。目前仍在继续评估生长情况,以观察HIV疾病的进一步进展是否会改变这些男孩的生长模式。

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